Neurobiological and Anti-Inflammatory Effects of a Deep Diaphragmatic Breathing Technique Based on Neofunctional Psychotherapy: A Pilot RCT.

Autor: Maniaci G; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Section of Psychiatry, (BiND), University of Palermo, Palermo, Italy.; Neo-Functional Psychotherapy Study Centre, Palermo, Italy.; Italian Society of Functional Psychotherapy (SIF), Naples, Italy., Daino M; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Section of Psychiatry, (BiND), University of Palermo, Palermo, Italy., Iapichino M; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Section of Psychiatry, (BiND), University of Palermo, Palermo, Italy., Giammanco A; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Section of Psychiatry, (BiND), University of Palermo, Palermo, Italy.; Department of Medical Sciences and Public Health, University of Cagliari, Palermo, Italy., Taormina C; Neo-Functional Psychotherapy Study Centre, Palermo, Italy.; Italian Society of Functional Psychotherapy (SIF), Naples, Italy., Bonura G; Neo-Functional Psychotherapy Study Centre, Palermo, Italy.; Italian Society of Functional Psychotherapy (SIF), Naples, Italy., Sardella Z; Neo-Functional Psychotherapy Study Centre, Palermo, Italy.; Italian Society of Functional Psychotherapy (SIF), Naples, Italy., Carolla G; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Section of Psychiatry, (BiND), University of Palermo, Palermo, Italy., Cammareri P; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Section of Psychiatry, (BiND), University of Palermo, Palermo, Italy., Sberna E; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Section of Psychiatry, (BiND), University of Palermo, Palermo, Italy., Clesi MF; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Section of Psychiatry, (BiND), University of Palermo, Palermo, Italy., Ferraro L; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Section of Psychiatry, (BiND), University of Palermo, Palermo, Italy., Gambino CM; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Clinical Molecular Medicine and Clinical Laboratory Medicine, (BiND), Institute of Clinical Biochemistry, University of Palermo, Palermo, Italy., Ciaccio M; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Clinical Molecular Medicine and Clinical Laboratory Medicine, (BiND), Institute of Clinical Biochemistry, University of Palermo, Palermo, Italy., Rispoli L; Italian Society of Functional Psychotherapy (SIF), Naples, Italy.; European School in Functional Psychotherapy (SEF), Naples, Italy., La Cascia C; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Section of Psychiatry, (BiND), University of Palermo, Palermo, Italy., La Barbera D; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Section of Psychiatry, (BiND), University of Palermo, Palermo, Italy., Quattrone D; Department of Biomedicine, Neuroscience and Advanced Diagnostic, Section of Psychiatry, (BiND), University of Palermo, Palermo, Italy.; Social, Genetics and Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Jazyk: angličtina
Zdroj: Stress and health : journal of the International Society for the Investigation of Stress [Stress Health] 2024 Dec; Vol. 40 (6), pp. e3503. Date of Electronic Publication: 2024 Nov 14.
DOI: 10.1002/smi.3503
Abstrakt: We examined the feasibility of using the neofunctional deep breathing (NDB) technique to reduce the allostatic load following the Trier Social Stress Test (TSST). Forty-four healthy subjects were randomised into experimental and control groups. Following the TSST procedure, participants underwent either a single session of NDB or an attention control intervention. The Procomp Infinity Biofeedback system measured breath per minute (BPM), respiratory amplitude, HRV linear domains, skin conductance, and trapezius muscle electromyographic activity. Cortisol and cytokine salivary concentrations, perceived stress, and anxiety levels were also assessed. These parameters were combined into an allostatic load index (ALI) to measure the intervention's effect. This pilot RCT demonstrated the feasibility of the study design and practicality of the intervention. The NDB group showed reduced ALI, increased respiratory abdominal amplitude, decreased BPM, increased HRV indicating parasympathetic activation, and decreased cortisol and inflammatory cytokines. This study highlighted the feasibility of testing the NDB technique in reducing allostatic load through a neurobiological and anti-inflammatory response after exposure to psychosocial stress. This protocol can represent a non-invasive therapeutic adjutant in disorders related to a dysregulation of the HPA axis or to an inflammatory state. Trial Registration: NCT04102813.
(© 2024 The Author(s). Stress and Health published by John Wiley & Sons Ltd.)
Databáze: MEDLINE
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