Influence of photobiomodulation and radiofrequency on the healing of pressure lesions in mice.

Autor: Vieceli AS; Laboratory of Assessment and Rehabilitation of the Locomotor Apparatus (LARAL), Department of Health Sciences, Universidade Federal de Santa Catarina, Rua Pedro João Pereira, 150, room 111, Mato Alto, Araranguá, Santa Catarin, CEP 88905-120, Brazil.; Postgraduate Program in Rehabilitation Sciences, Federal University of Santa Catarina (LARAL/UFSC), Rua Pedro João Pereira, 150, Araranguá, Santa Catarina, CEP 88905-120, Brazil., Silveira PCL; Laboratory of Experimental Physiopathology, Program of Postgraduate in Science of Health, Universidade do Extremo Sul Catarinense, Criciúma, Santa Catarina, 88806-000, Brazil., Zaccaron RP; Laboratory of Experimental Physiopathology, Program of Postgraduate in Science of Health, Universidade do Extremo Sul Catarinense, Criciúma, Santa Catarina, 88806-000, Brazil., Fonseca MCR; Postgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School of the University of São Paulo (USP), Av. dos Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil., Aguiar-Junior AS; Federal University of Santa Catarina, Laboratório Biologia do Exercício Físico (LaBioEx), Rua Pedro João Pereira, 150, Araranguá, Santa Catarina, CEP 88905-120, Brazil., Neves LMSD; Postgraduate Program in Rehabilitation and Functional Performance, Ribeirão Preto Medical School of the University of São Paulo (USP), Av. dos Bandeirantes, 3900, Ribeirão Preto, São Paulo, 14049-900, Brazil., Kuriki HU; Laboratory of Assessment and Rehabilitation of the Locomotor Apparatus (LARAL), Department of Health Sciences, Universidade Federal de Santa Catarina, Rua Pedro João Pereira, 150, room 111, Mato Alto, Araranguá, Santa Catarin, CEP 88905-120, Brazil.; Postgraduate Program in Rehabilitation Sciences, Federal University of Santa Catarina (LARAL/UFSC), Rua Pedro João Pereira, 150, Araranguá, Santa Catarina, CEP 88905-120, Brazil., Barbosa RI; Laboratory of Assessment and Rehabilitation of the Locomotor Apparatus (LARAL), Department of Health Sciences, Universidade Federal de Santa Catarina, Rua Pedro João Pereira, 150, room 111, Mato Alto, Araranguá, Santa Catarin, CEP 88905-120, Brazil.; Postgraduate Program in Rehabilitation Sciences, Federal University of Santa Catarina (LARAL/UFSC), Rua Pedro João Pereira, 150, Araranguá, Santa Catarina, CEP 88905-120, Brazil., Marcolino AM; Laboratory of Assessment and Rehabilitation of the Locomotor Apparatus (LARAL), Department of Health Sciences, Universidade Federal de Santa Catarina, Rua Pedro João Pereira, 150, room 111, Mato Alto, Araranguá, Santa Catarin, CEP 88905-120, Brazil. alexandre.marcolino@ufsc.br.; Postgraduate Program in Rehabilitation Sciences, Federal University of Santa Catarina (LARAL/UFSC), Rua Pedro João Pereira, 150, Araranguá, Santa Catarina, CEP 88905-120, Brazil. alexandre.marcolino@ufsc.br.
Jazyk: angličtina
Zdroj: Lasers in medical science [Lasers Med Sci] 2024 Nov 15; Vol. 39 (1), pp. 280. Date of Electronic Publication: 2024 Nov 15.
DOI: 10.1007/s10103-024-04226-5
Abstrakt: The objective of this study was to ascertain the impact of photobiomodulation and radiofrequency on the healing of pressure injuries in mice. A total of 70 animals were randomly assigned to seven experimental groups. A pressure injury was induced in the dorsal region of the mice by the application of two magnets. The photobiomodulation treatment was administered at a dosage of 3.6 J per session. In the radiofrequency group, the treatment time was four minutes and the power was 22 watts. The analyses included the lesion area, infrared thermography, and the collection of material for cytokine, histological, and histochemical analyses following euthanasia. In the macroscopic analyses, the 660 nm photobiomodulation group demonstrated superior outcomes in comparison to the control group. With regard to the microscopic analyses, the greatest difference between the groups was observed when TNF-α was evaluated in the photobiomodulation group. It can be observed that the groups irradiated by electrophysical means (i.e., a combination of radiofrequency with PBM 830 nm-660 nm) exhibited a positive influence on the repair process, with the greatest impact observed in the group irradiated by a combination of radiofrequency and 660 nm photobiomodulation.
Competing Interests: Declarations Conflict of interest The authors declare no conflict of interest.
(© 2024. The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature.)
Databáze: MEDLINE
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