Magnetoresponsive liposomes applications in nanomedicine: A comprehensive review.

Autor: Shahsavari S; Iran Nanotechnology Innovation Council, Nanoclub Elites Association, Tehran, Iran., Rad MB; Department of Biophysics, Institute of Biochemistry and Biophysics, University of Tehran, P.O. Box 13145-1384, Tehran, Iran., Hajiaghajani A; School of Electrical Engineering, Iran University of Science and Technology, Tehran 1684613114, Iran., Rostami M; Physics department E20, Technical University of Munich, Garching 85748, Germany., Hakimian F; Department of Biophysics, Institute of Biochemistry and Biophysics, University of Tehran, P.O. Box 13145-1384, Tehran, Iran., Jafarzadeh S; Department of Energy Conversion and Storage, Technical University of Denmark, Anker Engelunds Vej, Lyngby 2800 Kgs, Denmark., Hasany M; Department of Civil and Mechanical Engineering, Technical University of Denmark, Lyngby 2800 Kgs, Denmark., Collingwood JF; School of Engineering, University of Warwick, Coventry, UK., Aliakbari F; National Institute of Genetic Engineering and Biotechnology, Shahrak-e Pajoohesh, km 15 Tehran - Karaj Highway, P.O.Box:14965/161, Tehran, Iran; Molecular Medicine Research Group, Robarts Research Institute, Schulich School of Medicine and Dentistry, University of Western Ontario, London, ON, Canada., Fouladiha H; Department of Biotechnology, College of Science, University of Tehran, Tehran, Iran., Bardania H; Cellular and Molecular Research Center, Yasuj University of Medical Sciences, Yasuj, Iran. Electronic address: hasan.bardania@yums.ac.ir., Otzen DE; Interdisciplinary Nanoscience Centre (iNANO) and Department of Molecular Biology and Genetics, Aarhus University, Gustav Wieds Vej 14, Aarhus C DK-8000, Denmark. Electronic address: dao@inano.au.dk., Morshedi D; National Institute of Genetic Engineering and Biotechnology, Shahrak-e Pajoohesh, km 15 Tehran - Karaj Highway, P.O.Box:14965/161, Tehran, Iran. Electronic address: morshedi@nigeb.ac.ir.
Jazyk: angličtina
Zdroj: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Nov 13; Vol. 181, pp. 117665. Date of Electronic Publication: 2024 Nov 13.
DOI: 10.1016/j.biopha.2024.117665
Abstrakt: Safe and effective cancer therapy requires a suitable nanocarrier that can target particular sites, such as cancer cells, in a selective manner. With the tremendous growth in nanotechnology, liposomes, among various competing nanocarriers, have shown promising advances in cancer therapy. Magnetic nanoparticles and metal ions are wide-reaching candidates for conferring magnetic properties and for incorporation into liposomes. Combining liposomes with magnetic structures enables construction of magnetoresponsive liposomes, allowing stimuli-responsiveness to an alternating magnetic field, magnetic targeting, and tracking by magnetic resonance imaging, which could all occur in parallel. This review presents a comprehensive analysis of the practical advances and novel aspects of design, synthesis and engineering magnetoresponsive liposomes, emphasizing their diverse properties for various applications. Our work explores the innovative uses of these structures, extending beyond drug delivery to include smart contrast agents, cell labeling, biosensing, separation, and filtering. By comparing new findings with earlier studies, we showcase significant improvements in efficiency and uncover new potentials, setting a new benchmark for future research in the field of magnetoresponsive liposomes.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper
(Copyright © 2024. Published by Elsevier Masson SAS.)
Databáze: MEDLINE
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