Morphology of the human inner ear and vestibulocochlear nerve assessed using 7 T MRI.

Autor: Aphiwatthanasumet K; Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK. kingkarn.aphiwatthanasumet1@nottingham.ac.uk.; Department of Radiological Technology, Faculty of Allied Health Sciences, Naresuan University, Phitsanulok, Thailand. kingkarn.aphiwatthanasumet1@nottingham.ac.uk., Jethwa K; Department of Radiology, Nottingham University Hospitals NHS Foundation Trust, Nottingham, UK.; Sir Peter Mansfield Imaging Centre, School of Medicine, The University of Nottingham, Nottingham, UK., Glover P; Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK., O'Donoghue G; Department of Otolaryngology, Head and Neck Surgery, University of Nottingham, Nottingham, UK., Auer D; Sir Peter Mansfield Imaging Centre, School of Medicine, The University of Nottingham, Nottingham, UK., Gowland P; Sir Peter Mansfield Imaging Centre, School of Physics and Astronomy, University of Nottingham, Nottingham, UK.
Jazyk: angličtina
Zdroj: Magma (New York, N.Y.) [MAGMA] 2024 Nov 13. Date of Electronic Publication: 2024 Nov 13.
DOI: 10.1007/s10334-024-01213-3
Abstrakt: Objective: To optimize high-resolution 7 T MRI of the cochlea and measure normal cochlea and the cochlear nerve morphometry in vivo.
Materials and Methods: Eight volunteers with normal hearing were scanned at 7 T using an optimized protocol. Two neuroradiologists independently scored image quality. The basal turn lumen diameter (BTLD), height, width, length and volume of the cochlear, long (LD) and short (SD) diameter the calculated cross-sectional area (CSA) of the cochlear nerve were measured. Intra and inter-observer reliability was assessed using intraclass correlation (ICC).
Results: 3D T2W DRIVE combined with dielectric pads, allowed acquisition of high-resolution images showing detailed structures, such as the crista ampullaris in the semicircular canals. The overall grading scores from neuroradiologists were excellent. In the left ear, averaging over all subjects gave BTLD of 2.6 ± 0.05 mm, height of 4.9 ± 0.1 mm, width of 4.4 ± 0.2 mm, length of 36.5 ± 0.4 mm, volume of 0.16 ± 0.02 ml, LD of 1.31 ± 0.1 mm, SD of 1.06 ± 0.1 mm, and CSA of 1.1 ± 0.1 mm 2 . The right ear gave BTLD of 2.6 ± 0.04 mm, height of 4.9 ± 0.1 mm, width of 4.4 ± 0.3 mm, length of 35.5 ± 0.4 mm, volume of 0.16 ± 0.02 ml, LD of 1.29 ± 0.1 mm, SD of 1.07 ± 0.1 mm, and CSA of 1.10 ± 0.2 mm 2 . No statistically significant difference was found between the sides of the head (p-value > 0.05). The intra-observer reliability was high (0.77-0.94), while the inter-observer reliability varied from moderate to high (0.55-0.81).
Conclusion: 7 T MRI can provide excellent visualization of the internal structure of the cochlear and of the vestibulocochlear nerve in vivo.
Competing Interests: Declarations Conflict of interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Ethical approval This study was performed in line with the principles of the Declaration of Helsinki and approved by the University of Nottingham Faculty of Medicine & Health Sciences Research Ethics Committee (Ethics Reference No: H14082014/22).
(© 2024. The Author(s).)
Databáze: MEDLINE
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