Uncommon Coexistence of Eosinophilic Colitis, Asthma, and Elevated IgG4 Levels: A Case Report.

Autor:	Nguyen QH; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam., Pham TQN; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam., Lam HT; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam., Huynh TM; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam., Vu NTH; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam., Vo TTL; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam., Vo TD; Department of Internal Medicine, Faculty of Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.; Department of Gastroenterology, University Medical Center Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Jazyk:	angličtina
Zdroj:	International medical case reports journal [Int Med Case Rep J] 2024 Nov 07; Vol. 17, pp. 939-943. Date of Electronic Publication: 2024 Nov 07 (Print Publication: 2024).
DOI:	10.2147/IMCRJ.S482180
Abstrakt:	Purpose: Eosinophilic gastrointestinal diseases represent a rare and diverse group of conditions. Given that the pathogenesis of EoC is not well understood and is often linked to allergic conditions, this case underscores the necessity for further research into such unique presentations. The patient's prolonged gastrointestinal symptoms presented a significant diagnostic challenge, emphasizing the importance of ruling out various potential causes for elevated blood eosinophils. This exploration aims to enhance the understanding of such rare clinical scenarios and improve diagnostic accuracy in similar cases. Case Description: We present a unique case of a 57-year-old patient with a medical history of asthma and allergic rhinitis who presented recurrent abdominal pain, significant blood eosinophilia, and elevated levels of Immunoglobulin G4. After ruling out hematological and secondary causes of eosinophilia, a biopsy of the colon mucosa revealed an excess of tissue eosinophils, confirming the diagnosis of EoC. The patient responded well to corticosteroids and was subsequently maintained on montelukast, with no recurrence of symptoms over 3 months. Conclusion: This rare confluence of EoC, asthma, and high levels of serum IgG4 in a single patient contributes to our understanding of these complex and interconnected disorders. Competing Interests: Qui Huu Nguyen and Tram Que Nguyen Pham are co-first authors. The authors declare they have no competing interest for this study. (© 2024 Nguyen et al.)
Databáze:	MEDLINE
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