Unilateral adrenal metastases as an unusual primary presentation of hepatocellular carcinoma: a case report and literature review.

Autor: Ghouri RG; Pakistan Kidney and Liver Institute and Research Center., Sharjeel M; Pakistan Kidney and Liver Institute and Research Center., Naeem H; King Edward Medical University, Lahore, Pakistan., Abdullah S; Pakistan Kidney and Liver Institute and Research Center., Khalid UAR; King Edward Medical University, Lahore, Pakistan., Basil AM; Spinghar Medical University, Kabul, Afghanistan.
Jazyk: angličtina
Zdroj: Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2024 Aug 14; Vol. 86 (11), pp. 6726-6730. Date of Electronic Publication: 2024 Aug 14 (Print Publication: 2024).
DOI: 10.1097/MS9.0000000000002473
Abstrakt: Introduction and Importance: Adrenal metastases can rarely present as a solitary clinical manifestation among cases with underlying hepatocellular carcinoma (HCC).
Case Presentation: The authors present the case of a 53-year-old male with chronic liver disease due to chronic hepatitis C who presented with left flank pain. Imaging revealed a left-sided suprarenal mass. Following multidisciplinary assessment, the patient underwent left-sided nephrectomy and adrenalectomy, whereas histopathological correlation revealed microscopic foci of metastatic HCC in the resected gland. Postoperative abdominal imaging then revealed multifocal dysplastic lesions scattered through both the hepatic lobes. Subsequently, systemic treatment was initiated with sorafenib.
Clinical Discussion: These types of adrenal metastasis from the liver are extremely uncommon and need detailed evaluation of the liver and other potential metastatic sites. The choice of treatment will be indicated according to the type and site of the tumor.
Conclusion: This case highlights the significance of thorough evaluation and individualized management in HCC-associated adrenal metastasis.
Competing Interests: The authors declare no conflicts of interest.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.
(Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze: MEDLINE