Biliary atresia with rare associations: a case report and literature review.

Autor:	Zaben BA; Faculty of Medicine, Al-Quds University, Jerusalem., Abualrub AM; Faculty of Medicine, Al-Quds University, Jerusalem., Malhes WM; Faculty of Medicine, Al-Quds University, Jerusalem., Barabrah AM; Faculty of Medicine, Al-Quds University, Jerusalem., Tuqan AR; Faculty of Medicine, Al-Quds University, Jerusalem., Tahhan IA; Faculty of Medicine, Al-Quds University, Jerusalem., Amro W; Department of Pediatric Surgery, Palestine Medical Complex (PMC), Ramallah, Palestine.
Jazyk:	angličtina
Zdroj:	Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2024 Aug 08; Vol. 86 (11), pp. 6713-6716. Date of Electronic Publication: 2024 Aug 08 (Print Publication: 2024).
DOI:	10.1097/MS9.0000000000002173
Abstrakt:	Introduction and Importance: Biliary atresia is a rare, progressive cholangiopathy that affects newborns, causing jaundice and other manifestations of hyperbilirubinemia. The incidence is higher in Asia than in Europe. The only available treatment is a surgical operation called Kasai portoenterostomy. In this case, the authors highlighted rare congenital anomalies that came with biliary atresia. Case Presentation: A 10-day-old male infant was admitted to the hospital due to recurrent vomiting, yellowish skin, and scleral icterus. Laboratory investigations revealed elevated total serum and direct bilirubin levels. An atrophic gallbladder was observed on ultrasound. Intrahepatic cholangiography confirmed the diagnosis of biliary atresia, leading to the performance of a Kasai procedure. Additionally, the patient had intestinal malrotation and volvulus, which were managed with a Ladd's procedure. Following surgery, there was notable improvement in liver enzymes and bilirubin levels, and the patient was discharged after 7 days. The infant has been initiated on oral vitamins, ursodeoxycholic acid, and antibiotics. Clinical Discussion: Biliary atresia is a challenging condition characterized by progressive narrowing and fibrosis of the biliary tree. It is rarely associated with rare congenital anomalies like situs inversus totalis, intestinal malrotation, and volvulus. Diagnosis involves abdominal ultrasound and MRCG. The biliary atresia was managed by the Kasai procedure and the intestinal malrotation, and volvulus were managed by Ladd's procedure. Conclusion: This case report highlights the importance of considering rare associations such as situs inversus, intestinal malrotation and volvulus in the diagnosis of biliary atresia in newborn. Early diagnosis and prompt intervention are crucial for optimal outcomes. Competing Interests: The authors declare no conflicts of interest.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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