Quintuplet pregnancy: a case report from Pakistan.

Autor:	Qayyum SN; Bacha Khan Medical College, Mardan., Alamgir E; University Medical and Dental College, Faisalabad., Alamgir I; University Medical and Dental College, Faisalabad., Khan GA; Bacha Khan Medical College, Mardan., Alamgir U; University Medical and Dental College, Faisalabad., Rehan M; Al-Nafees Medical College and Hospital, Islamabad, Pakistan., Noori S; Faculty of Medicine, Nangarhar University, Nangarhar, Afghanistan.
Jazyk:	angličtina
Zdroj:	Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2024 Sep 24; Vol. 86 (11), pp. 6814-6818. Date of Electronic Publication: 2024 Sep 24 (Print Publication: 2024).
DOI:	10.1097/MS9.0000000000002598
Abstrakt:	Introduction and Importance: Quintuplet pregnancies are exceptionally rare outcomes of fertility treatments, that is clomiphene citrate therapy. These high-order multiple pregnancies carry significant risks for both maternal and neonatal health, necessitating specialized care to manage complications effectively. Case Presentation: A 26-year-old woman, gravida three para two, presented with preterm labor at 32 weeks gestation following clomiphene citrate self-medication. Diagnosed with quintuplets, she underwent an emergency cesarean section at Allied-1 Hospital, Faisalabad, delivering five neonates alive. Unfortunately, all five neonates succumbed to death due to perinatal asphyxia, three within 24 h and two on the third day. Clinical Discussion: Higher-order multiple pregnancies, such as quintuplets, are associated with increased risks of obstetric complications, including pre-eclampsia, gestational diabetes, and fetal growth restriction. Preterm birth further exacerbates the risk of neonatal complications like respiratory distress syndrome, perinatal asphyxia, and death. The patient's care highlights the challenges of managing such pregnancies in resource-limited settings, emphasizing the need for specialized antenatal and neonatal care facilities. Conclusion: This case highlights the critical need for advanced medical care in managing high-order multiple pregnancies. The outcomes reflect the significant challenges posed by preterm labor and neonatal complications in quintuplet pregnancies. There is the need for enhanced antenatal care, healthcare infrastructure, and multidisciplinary teams for the efficient management of high-order multiple pregnancies in Pakistan, where neonatal and maternal mortality rates are surprisingly high. Competing Interests: The authors declare no conflict of interest.Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article. (Copyright © 2024 The Author(s). Published by Wolters Kluwer Health, Inc.)
Databáze:	MEDLINE
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