Remimazolam Anesthesia for Modified Electroconvulsive Therapy Mitigates Postoperative Agitation.

Autor: Shimono S; Perioperative Medicine, Division of Anesthesiology, Showa University School of Dentistry, Tokyo, JPN., Shakuo T; Anesthesiology, Showa University Northern Yokohama Hospital, Yokohama, JPN., Yamamura A; Anesthesiology, Showa University Northern Yokohama Hospital, Yokohama, JPN., Hashimoto M; Anesthesiology, Showa University Northern Yokohama Hospital, Yokohama, JPN., Masuda R; Perioperative Medicine, Division of Anesthesiology, Showa University School of Dentistry, Tokyo, JPN., Shida K; Anesthesiology, Showa University Northern Yokohama Hospital, Yokohama, JPN.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Oct 07; Vol. 16 (10), pp. e71037. Date of Electronic Publication: 2024 Oct 07 (Print Publication: 2024).
DOI: 10.7759/cureus.71037
Abstrakt: Postoperative complications, such as immediate postoperative blood pressure elevation, agitation, and delirium, have been associated with modified electroconvulsive therapy (mECT). Remimazolam may reduce postoperative delirium; however, there are no reports of its use in mECT. Herein, we present a case of effective convulsions and calm arousal with remimazolam in a patient with a history of postoperative agitation. The patient was a 45-year-old man who was diagnosed with severe depression and psychotic symptoms and was treated with electroconvulsive therapy (ECT). Owing to previous episodes of agitation upon awakening, remimazolam and suxamethonium were administered, and mECT was performed under general anesthesia to ensure effective convulsions and calm awakening. Intraoperative vital signs were normal, with no signs of agitation post-treatment. Remimazolam administration for general anesthesia induction for mECT effectively induced convulsions and suppressed postoperative excitation. However, its effect on convulsions during mECT remains unclear, warranting further investigation.
Competing Interests: Human subjects: All authors have confirmed that this study did not involve human participants or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Shimono et al.)
Databáze: MEDLINE