Acute Kidney Injury Secondary to Hypertension-Related Thrombotic Microangiopathy: A Case Report and Literature Review.

Autor: Blatsos A; Department of Renal Medicine, Portsmouth Hospitals University National Health Service (NHS) Trust, Portsmouth, GBR., Alalwan AA; Department of Renal Medicine, Portsmouth Hospitals University National Health Service (NHS) Trust, Portsmouth, GBR., Razeem M; Department of Renal Medicine, Portsmouth Hospitals University National Health Service (NHS) Trust, Portsmouth, GBR., Laird A; Department of Renal Medicine, Portsmouth Hospitals University National Health Service (NHS) Trust, Portsmouth, GBR.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Oct 08; Vol. 16 (10), pp. e71067. Date of Electronic Publication: 2024 Oct 08 (Print Publication: 2024).
DOI: 10.7759/cureus.71067
Abstrakt: The presence of acute kidney injuries (AKIs) in adults with microangiopathic hemolytic anemia and thrombocytopenia poses diagnostic and therapeutic challenges, as there are numerous causes that cannot always be rapidly differentiated. Treatment options vary widely, ranging from urgent treatments such as plasma exchange and anticomplement therapy to observation and supportive care. We report a case of AKI secondary to hypertension-related thrombotic microangiopathy and describe the clinical course from presentation to diagnosis and treatment. The patient remained hemodialysis-dependent despite attempts to control the blood pressure and administer anticomplement treatment.
Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Blatsos et al.)
Databáze: MEDLINE