Achalasia: Diagnosis and Management.

Autor: Provenza CG; University of Massachusetts Chan Medical School, Baystate Medical Center, Springfield, MA, USA., Romanelli JR; University of Massachusetts Chan Medical School, Baystate Medical Center, Springfield, MA, USA. Electronic address: John.Romanelli@Baystatehealth.org.
Jazyk: angličtina
Zdroj: The Surgical clinics of North America [Surg Clin North Am] 2025 Feb; Vol. 105 (1), pp. 143-158. Date of Electronic Publication: 2024 Sep 06.
DOI: 10.1016/j.suc.2024.06.011
Abstrakt: Achalasia is an incurable condition of the esophagus involving the inflammation and degeneration of inhibitory neurons of the lower esophageal sphincter (LES) resulting in failure of the LES to relax. Typical symptoms of achalasia are dysphagia, retrosternal chest pain, regurgitation, and weight loss. Three studies are typically required for the diagnosis of achalasia: barium swallow, high-resolution esophageal manometry, and esophagogastroduodenoscopy. Differential diagnosis includes gastroesophageal reflux disease, pseudoachalasia, neoplasm, and nonachalasia esophageal motility disorders such as scleroderma, jackhammer esophagus, distal esophageal spasm, and nutcracker esophagus.
Competing Interests: Disclosure Dr C.G. Provenza has no disclosures to report. Dr J.R. Romanelli is a proctor for Erbe USA and in so doing teaches the POEM procedure, which is relevant to this study, but it did not contribute to the creation of this study. He also consults for New View Surgical but this is not relevant to this study.
(Copyright © 2024 Elsevier Inc. All rights reserved.)
Databáze: MEDLINE