| Autor: |
Saito K; Laboratory of Veterinary Reproduction, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan., Tanaka T; Laboratory of Veterinary Reproduction, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan., Endo N; Laboratory of Veterinary Reproduction, Tokyo University of Agriculture and Technology, Tokyo 183-8509, Japan. |
| Jazyk: |
angličtina |
| Zdroj: |
The Journal of reproduction and development [J Reprod Dev] 2024 Dec 13; Vol. 70 (6), pp. 423-426. Date of Electronic Publication: 2024 Nov 10. |
| DOI: |
10.1262/jrd.2024-083 |
| Abstrakt: |
Progesterone (P4)-impregnated controlled internal drug-releasing device for goats and sheep (CIDR-G) is used in the estrus synchronization protocol; however, it is not commercially available in Japan. In this study, we investigated whether a modification of CIDR-B, designed for cattle, could be used as a P4 release device for synchronizing estrus in goats. An in vitro analysis showed that the dissolution rate was not significantly different between CIDR-G and modified CIDR-B (CIDR-M). The administration of CIDR-G or CIDR-M to dairy goats resulted in plasma P4 concentrations being maintained at the functional luteal phase levels (>2 ng/ml) in both groups for 12 days after administration. However, P4 concentrations at 2, 4, and 8 days after the administration of CIDR-G were significantly higher than those after the administration of CIDR-M. These results suggest that the CIDR-M examined in this study can maintain P4 levels for 12 days after its administration as a P4 release device. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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