An alternative approach for compliance testing of food and skin contact silicone elastomers by specific determination of volatile cyclic siloxane oligomers via GC-FID.

Autor: Eckardt M; Laboratory Lommatzsch & Säger GmbH, Gottfried-Hagen-Str. 60-62, 51105, Cologne, Germany. Electronic address: eckardt@mosh-moah.de., Seidel AK; TU Dresden, Chair of Food Science and Food Contact Materials, Bergstr. 66, 01062, Dresden, Germany., Säger S; Laboratory Lommatzsch & Säger GmbH, Gottfried-Hagen-Str. 60-62, 51105, Cologne, Germany., Simat TJ; TU Dresden, Chair of Food Science and Food Contact Materials, Bergstr. 66, 01062, Dresden, Germany.
Jazyk: angličtina
Zdroj: Talanta [Talanta] 2024 Nov 01; Vol. 283, pp. 127145. Date of Electronic Publication: 2024 Nov 01.
DOI: 10.1016/j.talanta.2024.127145
Abstrakt: To date, silicone elastomers intended for food and skin contact are considered compliant as long as their weight loss during a thermal treatment (200 °C, 4 h) is below 0.5 wt%. The common assumption is that this weight loss is caused almost entirely by potentially harmful volatile siloxane oligomers. The present study questions this assumption, first time balancing the initial content and the thermal removal of volatile siloxanes in 48 silicone materials. A GC-FID method for a specific determination of linear (L4 up to L24) and cyclic siloxane oligomers (D4 up to D25) was developed and validated against 1 H NMR and thermal desorption GC-MS analysis. All samples contained significant amounts of cyclic siloxanes, while linear trimethylsiloxy terminated oligomers were not detected. Only a weak correlation between the weight loss after thermal treatment and the initial content of cyclic siloxanes was determined for most samples. However, rapid adsorption of humidity from ambient air and its incomplete removal during sample conditioning were determined as crucial aspects in conventional gravimetric compliance testing for silicone articles. Consequently, the specific determination of volatile cyclic siloxane profiles via GC-FID is suggested as the more reliable approach for a compliance decision.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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