Effects of metallic dust on Nile tilapia: Exploring the relationship between metal bioaccumulation, metallothionein levels, and oxidative stress responses.

Autor: Maraschi AC; Departamento de Ciências Fisiológicas (DCF), Centro de Ciências Biológicas e da Saúde (CCBS), Universidade Federal de São Carlos (UFSCar), 13565-905 São Carlos, São Paulo, Brazil., Adorno HA; Departamento de Ciências Fisiológicas (DCF), Centro de Ciências Biológicas e da Saúde (CCBS), Universidade Federal de São Carlos (UFSCar), 13565-905 São Carlos, São Paulo, Brazil; Programa de Pós-Graduação em Ciências Ambientais, Universidade Federal de São Carlos (PPGCAm/UFSCar), 13565-905 São Carlos, São Paulo, Brazil., Gonçalves YC; Departamento de Ciências Fisiológicas (DCF), Centro de Ciências Biológicas e da Saúde (CCBS), Universidade Federal de São Carlos (UFSCar), 13565-905 São Carlos, São Paulo, Brazil; Programa Interinstitucional de Pós-Graduação em Ciências Fisiológicas, Universidade Federal de São Carlos/Universidade Estadual Paulista (PIPGCF UFSCar/UNESP), 13565-905 São Carlos, São Paulo, Brazil., Souza IC; Departamento de Ciências Fisiológicas (DCF), Centro de Ciências Biológicas e da Saúde (CCBS), Universidade Federal de São Carlos (UFSCar), 13565-905 São Carlos, São Paulo, Brazil., Monferrán MV; ICYTAC, Instituto de Ciencia y Tecnología de Alimentos Córdoba, CONICET and Dpto. Qca. Orgánica, Fac. Cs. Químicas, Universidad Nacional de Córdoba, Ciudad Universitaria, 5000 Córdoba, Argentina., Wunderlin DA; ICYTAC, Instituto de Ciencia y Tecnología de Alimentos Córdoba, CONICET and Dpto. Qca. Orgánica, Fac. Cs. Químicas, Universidad Nacional de Córdoba, Ciudad Universitaria, 5000 Córdoba, Argentina., Fernandes MN; Departamento de Ciências Fisiológicas (DCF), Centro de Ciências Biológicas e da Saúde (CCBS), Universidade Federal de São Carlos (UFSCar), 13565-905 São Carlos, São Paulo, Brazil., Monteiro DA; Departamento de Ciências Fisiológicas (DCF), Centro de Ciências Biológicas e da Saúde (CCBS), Universidade Federal de São Carlos (UFSCar), 13565-905 São Carlos, São Paulo, Brazil. Electronic address: dianamonteiro@ufscar.br.
Jazyk: angličtina
Zdroj: The Science of the total environment [Sci Total Environ] 2024 Dec 15; Vol. 956, pp. 177423. Date of Electronic Publication: 2024 Nov 10.
DOI: 10.1016/j.scitotenv.2024.177423
Abstrakt: Settleable atmospheric particulate matter (SePM), from steelmaking processes, contains a complex mixture of metals, metalloids, and metallic nanoparticles. The SePM is released airborne and disperses in water, representing a significant threat to aquatic life, particularly fish. This study investigated the effects of a sublethal and environmentally relevant concentration of SePM (1 g·L -1 ) for 96 h in the gill, liver, kidney, and white muscle of Nile tilapia (Oreochromis niloticus), employing exposure and effect biomarkers to test causality between metal accumulation and biochemical responses. The gills and liver showed the highest bioaccumulation of metals and integrated response index value, indicating susceptibility to metal accumulation. However, the gills produce a protective mucus layer that may mitigate metal toxicity. The kidneys and muscle tissue also showed bioaccumulation of metals, although to a lesser extent. The liver and kidneys experienced oxidative stress, characterized by reduced metallothionein and glutathione levels, as well as damage to lipids, proteins, and DNA. The accumulation of less-studied metals, particularly Rare Earth Elements (REEs), compromised the integrity of biomolecules in these tissues. In conclusion, the complex dynamics of metal bioaccumulation in Nile tilapia exposed to SePM reveal varied tissue responses and primary effects like oxidative damage. They also highlight the need for further research and regulation of other metals and their potential impacts on aquatic ecosystems and human health.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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