Raising the Bar: Progress in 3D-Printed Hybrid Bone Scaffolds for Clinical Applications: A Review.

Autor: Khan AR; Department of Interventional and Vascular Surgery, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.; National United Engineering Laboratory for Biomedical Material Modification, Branden Industrial Park, Qihe Economic & Development Zone, Dezhou, China., Grewal NS; Department of Mechanical Engineering, Guru Kashi University, Talwandi Sabo, India., Jun Z; Research Center for Translational Medicine, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China., Tawfiq FMO; Mathematics Department, College of Science, King Saud University, Riyadh, Saudi Arabia., Tchier F; Mathematics Department, College of Science, King Saud University, Riyadh, Saudi Arabia., Muhammad Zulqarnain R; Department of Mathematics, Saveetha School of Engineering, SIMATS Thandalam, Chennai, India., Zhang HJ; Department of Interventional and Vascular Surgery, Shanghai Tenth People's Hospital, School of Medicine, Tongji University, Shanghai, China.; National United Engineering Laboratory for Biomedical Material Modification, Branden Industrial Park, Qihe Economic & Development Zone, Dezhou, China.
Jazyk: angličtina
Zdroj: Cell transplantation [Cell Transplant] 2024 Jan-Dec; Vol. 33, pp. 9636897241273562.
DOI: 10.1177/09636897241273562
Abstrakt: Damage to bones resulting from trauma and tumors poses a significant challenge to human health. Consequently, current research in bone damage healing centers on developing three-dimensional (3D) scaffolding materials that facilitate and enhance the regeneration of fractured bone tissues. In this context, the careful selection of materials and preparation processes is essential for creating demanding scaffolds for bone tissue engineering. This is done to optimize the regeneration of fractured bones. This study comprehensively analyses the latest scientific advancements and difficulties in developing scaffolds for bone tissue creation. Initially, we clarified the composition and process by which bone tissue repairs itself. The review summarizes the primary uses of materials, both inorganic and organic, in scaffolds for bone tissue engineering. In addition, we present a comprehensive study of the most recent advancements in the mainstream techniques used to prepare scaffolds for bone tissue engineering. We also examine the distinct advantages of each method in great detail. This article thoroughly examines potential paths and obstacles in bone tissue engineering scaffolds for clinical applications.
Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze: MEDLINE