A quality assessment and systematic review of clinical practice guidelines on hormone replacement therapy for menopause using the AGREE II instrument.

Autor: Roman MP; Mother and Child Department, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 8 Victor Babes Str, Cluj-Napoca 400347, Romania; 2(nd) Obstetrics and Gynaecology Clinical Section, Cluj County Emergency Clinical Hospital, 55-57 21(st) of December 1989 Bld, Cluj-Napoca 400124, Romania., Ciortea R; Mother and Child Department, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 8 Victor Babes Str, Cluj-Napoca 400347, Romania; 2(nd) Obstetrics and Gynaecology Clinical Section, Cluj County Emergency Clinical Hospital, 55-57 21(st) of December 1989 Bld, Cluj-Napoca 400124, Romania. Electronic address: r_ciortea@yahoo.com., Doumouchtsis SK; Department of Obstetrics and Gynaecology, Epsom and St. Helier University Hospitals NHS Trust, Dorking Rd, Epsom KT187EG, United Kingdom; St. George's University of London, Cranmer Terrace, London SW17 0RE, United Kingdom; Laboratory of Experimental Surgery and Surgical Research 'N.S. Christeas', National and Kapodistrian University of Athens, Medical School, 75 Mikras Asias Str, Goudi, Athens 11527, Greece; School of Medicine, American University of the Caribbean, 1 University Drive at Jordan Rd, Cupecoy, Sint Maarten; School of Medicine, Ross University, 10315 USA Today Way, Miramar, FL 33025 USA., Din R; Mother and Child Department, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 8 Victor Babes Str, Cluj-Napoca 400347, Romania. Electronic address: roxicrainic@gmail.com., Măluţan AM; Mother and Child Department, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 8 Victor Babes Str, Cluj-Napoca 400347, Romania; 2(nd) Obstetrics and Gynaecology Clinical Section, Cluj County Emergency Clinical Hospital, 55-57 21(st) of December 1989 Bld, Cluj-Napoca 400124, Romania., Bucuri CE; Mother and Child Department, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 8 Victor Babes Str, Cluj-Napoca 400347, Romania; Military Emergency Hospital 'Dr. Constantin Papilian', 22 General Traian Moșoiu Str, Cluj-Napoca 400132, Romania., Căşeriu EA; Colentina Clinical Hospital, 19-21 Ștefan cel Mare Rd, Bucharest 020125, Romania., Ormindean CM; Mother and Child Department, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 8 Victor Babes Str, Cluj-Napoca 400347, Romania; 2(nd) Obstetrics and Gynaecology Clinical Section, Cluj County Emergency Clinical Hospital, 55-57 21(st) of December 1989 Bld, Cluj-Napoca 400124, Romania., Nati ID; Mother and Child Department, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 8 Victor Babes Str, Cluj-Napoca 400347, Romania; 2(nd) Obstetrics and Gynaecology Clinical Section, Cluj County Emergency Clinical Hospital, 55-57 21(st) of December 1989 Bld, Cluj-Napoca 400124, Romania., Suciu VE; Mother and Child Department, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 8 Victor Babes Str, Cluj-Napoca 400347, Romania., Mihu D; Mother and Child Department, 'Iuliu Hațieganu' University of Medicine and Pharmacy, 8 Victor Babes Str, Cluj-Napoca 400347, Romania; 2(nd) Obstetrics and Gynaecology Clinical Section, Cluj County Emergency Clinical Hospital, 55-57 21(st) of December 1989 Bld, Cluj-Napoca 400124, Romania.
Jazyk: angličtina
Zdroj: European journal of obstetrics, gynecology, and reproductive biology [Eur J Obstet Gynecol Reprod Biol] 2024 Dec; Vol. 303, pp. 294-301. Date of Electronic Publication: 2024 Nov 02.
DOI: 10.1016/j.ejogrb.2024.10.046
Abstrakt: Clinical Practice Guidelines (CPGs) have an indispensable role in guiding the selection of treatments for menopause. Variations in guidelines can impact treatments and health outcomes. The aim of this study was to assess CPGs on hormone replacement therapy (HRT) for menopause, systematically reviewing their quality and compiling recommendations for HRT usage. Embase, Scopus, MedLine, Geneva Foundation for Medical Education and Research databases were searched to identify relevant publications. CPGs published in English language, focusing specifically on HRT for menopause were included in the analysis. Four reviewers assessed the quality of the included CPGs using the Appraisal of Guidelines for Research & Evaluation II (AGREE II) instrument and compiled congruent as well as contradictory recommendations. Nine guidelines met the inclusion criteria. The National Institute for Health and Care Excellence (NICE), the Endocrine Society and The Association of the Scientific Medical Societies guidelines were deemed to have the highest quality and are recommended without modifications. Out of 300+ extracted recommendations, merely 17 showed consistency, overlapping in at least two CPGs. The recommendations were categorized into three domains: treatment considerations, impact of HRT on non-reproductive organ systems, and the associations of HRT with cancer. The included CPGs exhibited the highest scores in the "Clarity of presentation" and "Scope and purpose" AGREE II domains. This study found variation in recommendations and quality of CPG on HRT for menopause. Notably, only a small fraction of recommendations showed consistency across guidelines, highlighting the variability in HRT management. Efforts to improve the quality of CPGs in this area are essential to optimize patient care and outcomes in menopausal women receiving HRT.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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