Current trends and challenges in infective endocarditis.
| Autor: | Patel SK; Temerty Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada., Hassan SMA; Division of Cardiac Surgery, St. Michael's Hospital of Unity Health Toronto, Toronto, Ontario., Côté M; Université de Sherbrooke, Centre de formation médicale du Nouveau Brunswick, Moncton., Leis B; Department of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada., Yanagawa B; Division of Cardiac Surgery, St. Michael's Hospital of Unity Health Toronto, Toronto, Ontario. |
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| Jazyk: | angličtina |
| Zdroj: | Current opinion in cardiology [Curr Opin Cardiol] 2024 Nov 08. Date of Electronic Publication: 2024 Nov 08. |
| DOI: | 10.1097/HCO.0000000000001192 |
| Abstrakt: | Purpose of Review: Infective endocarditis (IE) is a complex disease with increasing global incidence. This review explores recent trends in IE infection patterns, including healthcare-associated IE (HAIE), drug-use-associated IE (DUA-IE), multidrug-resistant organisms (MDROs), and challenges in managing prosthetic valve and device-related infections. Recent Findings: Staphylococcus aureus has emerged as the leading cause of IE, especially in HAIE and DUA-IE cases. Increasingly prevalent MDROs, such as methicillin-resistant Staphylococcus aureus and vancomycin-resistant enterococci, pose further clinical challenges. Advances in molecular diagnostics have improved the detection of culture-negative endocarditis. The introduction of the AngioVAC percutaneous aspiration device promises to change the management of right and possibly some left sided IE. Multidisciplinary team management and early surgery have demonstrated improved outcomes including partnerships with psychiatry and addictions services for those with intravenous DUA-IE. Summary: IE presents significant diagnostic and therapeutic challenges due to evolving infection patterns, MDROs, and HAIE. Early diagnosis using advanced imaging, appropriate early antimicrobial therapy, and multidisciplinary care, including timely surgery, are critical for optimizing patient outcomes. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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