Transition to Enteral Triazole Antifungal Therapy for Pediatric Invasive Candidiasis: Secondary Analysis of a Multicenter Cohort Study Conducted by the Pediatric Fungal Network.

Autor:	Bucayu RFT; Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA.; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Boge CLK; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA., Yildirim I; Department of Pediatrics, Yale University School of Medicine, CT, USA.; Yale Institute for Global Health, Yale University, New Haven, CT, USA.; Yale Center for Infection and Immunity, New Haven, CT, USA.; Department of Epidemiology, Yale School of Public Health, New Haven, CT, USA., Avilés-Robles M; Department of Infectious Diseases, Hospital Infantil de México Federico Gómez, Mexico City, Mexico., Vora SB; Department of Pediatrics, University of Washington and Division of Infectious Diseases, Seattle Children's Hospital, Seattle, WA, USA., Berman DM; Medical Affairs, Karius, Inc., Sharma TS; Division of Infectious Diseases, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA., Sung L; Division of Haematology/Oncology, The Hospital for Sick Children, Toronto, Canada., Castagnola E; Department of Pediatrics, IRCCS Istituto Giannina Gaslini, Genoa, Italy., Palazzi DL; Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA., Danziger-Isakov L; Department of Pediatrics, Cincinnati Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH, USA., Yin DE; Department of Pediatrics, Children's Mercy Kansas City, University of Missouri-Kansas City, MO, USA., Roilides E; Infectious Diseases Unit, 3rd Department of Pediatrics, Aristotle University and Hippokration Hospital, Thessaloniki, Greece., Maron G; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA., Tribble AC; Department of Pediatrics, Division of Pediatric Infectious Diseases, C.S. Mott Children's Hospital, University of Michigan , Ann Arbor, MI, USA., Soler-Palacin P; Pediatric Infectious Diseases and Immunodeficiencies Unit, Hospital Universitari Vall d'Hebron, Barcelona, Catalonia, Spain., López-Medina E; Centro de Estudios en Infectología Pediátrica, Clínica Imbanaco Grupo Quirónsalud and Universidad del Valle, Cali, Colombia., Romero J; National Center for Immunization and Respiratory Diseases; Centers for Disease Control and Prevention, Atlanta, GA, USA., Belani K; Pediatric Infectious Diseases, Children's Minnesota, Minneapolis, Minnesota, USA., Arrieta AC; Department of Infectious Diseases, Children's Hospital of Orange County, Orange, CA, USA.; Department of Pediatrics, University of California Irvine, Irvine, CA, USA., Carlesse F; Instituto de Oncologia Pediatrica-IOP/GRAACC-UNIFESP, São Paulo, Brazil., Nolt D; Division of Pediatric Infectious Diseases, Oregon Health & Science University and Doernbecher Children's Hospital, Portland, OR, USA., Halasa N; Department of Pediatrics, Vanderbilt University Medical Center and Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA., Dulek D; Department of Pediatrics, Vanderbilt University Medical Center and Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, USA., Rajan S; Division of Pediatric Infectious Diseases, Northwell, Cohen Children's Medical Center, New Hyde Park, NY, USA., Muller WJ; Department of Pediatrics, Ann & Robert H. Lurie Children's Hospital of Chicago and Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Ardura MI; Division of Infectious Diseases and Host Defense Program, Department of Pediatrics, Nationwide Children's Hospital and The Ohio State University, Columbus, OH, USA., Pong A; Department of Pediatrics, University of California San Diego and Rady Children's Hospital San Diego, San Diego, CA, USA., Gonzalez BE; Center for Pediatric Infectious Diseases, Cleveland Clinic Foundation, Cleveland, OH, USA., Salvatore CM; Division of Pediatric Infectious Diseases, Weill Cornell Medicine and Komansky Children's Hospital, New York, NY, USA., Huppler AR; Department of Pediatrics, Medical College of Wisconsin and Children's Wisconsin, Milwaukee, WI, USA., Aftandilian C; Division of Pediatric Hematology, Oncology, Stem Cell Transplant and Regenerative Medicine, Stanford University School of Medicine, Palo Alto, CA, USA., Abzug MJ; Department of Pediatrics, University of Colorado School of Medicine and Children's Hospital Colorado, Aurora, CO, USA., Chakrabarti A; Doodhadhar Burfani Hospital and Research Institute, Haridwar, India., Green M; Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, PA, USA., Lutsar I; Department of Microbiology, University of Tartu, Tartu, Estonia., Knackstedt ED; Division of Pediatric Infectious Diseases, University of Utah, Salt Lake City, UT, USA., Johnson SK; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Steinbach WJ; Department of Pediatrics, University of Arkansas for Medical Sciences, Little Rock, AR, USA., Fisher BT; Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Biostatistics, Epidemiology and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Wattier RL; Department of Pediatrics, University of California San Francisco, San Francisco, CA, USA.
Jazyk:	angličtina
Zdroj:	Journal of the Pediatric Infectious Diseases Society [J Pediatric Infect Dis Soc] 2024 Nov 08. Date of Electronic Publication: 2024 Nov 08.
DOI:	10.1093/jpids/piae116
Abstrakt:	Of 319 children with invasive candidiasis, 67 (21%) transitioned from intravenous to enteral antifungal therapy. Eight (12%) transitioned back to intravenous antifungal therapy, one due to perceived treatment failure defined by clinical progression or worsening. Global treatment response at study completion was success in 66 participants transitioned to enteral therapy. (© The Author(s) 2024. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For commercial re-use, please contact reprints@oup.com for reprints and translation rights for reprints. All other permissions can be obtained through our RightsLink service via the Permissions link on the article page on our site—for further information please contact journals.permissions@oup.com.)
Databáze:	MEDLINE
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