The Link Between Metabolic Dysfunction-Associated Steatotic Liver Disease and Gastroesophageal Reflux Disease.

Autor:	Dutta P; Internal Medicine, Trinity Health, Ann Arbor, USA., Annoor A; Oncology, Texas Oncology, Dallas, USA., Dey P; Internal Medicine, Chittagong Medical College, Chattagram, BGD., Sultana J; Internal Medicine, Comilla Medical College, Cumilla, BGD., Mokbul MI; Internal Medicine, Dhaka Medical College, Dhaka, BGD., Naurin SA; Internal Medicine, Ibrahim Medical College, Dhaka, BGD., Roy R; Internal Medicine, Ragib-Rabeya Medical College and Hospital, Chittagong, BGD., Simona SY; Internal Medicine, Khulna Medical College, Khulna, BGD., Dutta J; Internal Medicine, Comilla Medical College, Cumilla, BGD., Mazumder T; Family Medicine, Zainul Haque Sikder Women's Medical College and Hospital, Dhaka, BGD., Masud F; Internal Medicine, Shaheed Ziaur Rahman Medical College, Dhaka, BGD.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Oct 08; Vol. 16 (10), pp. e71095. Date of Electronic Publication: 2024 Oct 08 (Print Publication: 2024).
DOI:	10.7759/cureus.71095
Abstrakt:	Metabolic dysfunction-associated steatotic liver disease (MASLD), formerly nonalcoholic fatty liver disease (NAFLD), and gastroesophageal reflux disease (GERD) are prevalent chronic conditions with escalating global incidence. This study delves into the intricate interplay between MASLD and GERD. The primary objective is to comprehensively explore the association between MASLD and GERD, investigating how various factors contribute to the coexistence and potential exacerbation of these conditions. We conducted a literature search in PubMed and Google Scholar of only human studies over the past 10 years. The search included systematic review, meta-analysis, editorial, and cross-sectional studies of patients with MASLD and GERD. The prevalence of GERD in patients with MASLD was higher, with various risk factors coming into play. Obesity was identified as an independent risk factor for both GERD and MASLD. However, obese patients predominantly had higher disease progression. Lifestyle factors like physical activity and dietary modifications emerge as promising strategies to mitigate risk. Competing Interests: Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Dutta et al.)
Databáze:	MEDLINE
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