Regional variations in psoriatic arthritis: Insights from a nationwide multicenter analysis in Türkiye.

Autor:	Kılıç E; Rheumatology Clinic, Kanuni Training and Research Hospital, Trabzon, Türkiye., Kılıç G; Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Karadeniz Technical University Faculty of Medicine, Trabzon, Türkiye., Tekeoğlu İ; Department of Physical Medicine and Rehabilitation, Division of Rheumatology and Immunology, Sakarya University Faculty of Medicine, Sakarya, Türkiye., Sargın B; Rheumatology Clinic, Aydın State Hospital, Aydın, Türkiye., Acer Kasman S; Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Marmara University Faculty of Medicine, İstanbul, Türkiye., Alkan H; Department of Physical Medicine and Rehabilitation, Pamukkale University Faculty of Medicine, Denizli, Türkiye., Şahin N; Department of Physical Medicine and Rehabilitation, Balıkesir University Faculty of Medicine, Balıkesir, Türkiye., Cengiz G; Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Erciyes University Faculty of Medicine, Kayseri, Türkiye., Cüzdan N; Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Hatay Mustafa Kemal University Faculty of Medicine, Hatay, Türkiye., Albayrak Gezer İ; Rheumatology Clinic, Kanuni Training and Research Hospital, Trabzon, Türkiye., Keskin D; Department of Physical Medicine and Rehabilitation, Kırıkkale University Faculty of Medicine, Kırıkkale, Türkiye., Mülkoğlu C; Department of Physical Medicine and Rehabilitation, Health Sciences of University, Ankara Training and Research Hospital, Ankara, Türkiye., Reşorlu H; Department of Physical Medicine and Rehabilitation, Çanakkale Onsekiz Mart University Faculty of Medicine, Çanakkale, Türkiye., Sunar İ; Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Ankara University Faculty of Medicine, Ankara, Türkiye., Bal A; Department of Physical Medicine and Rehabilitation, University of Health Sciences, Dışkapı Yıldırım Beyazıt Training and Research Hospital, Ankara, Türkiye., Duruöz MT; Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Marmara University Faculty of Medicine, İstanbul, Türkiye., Küçükakkaş O; NMC Speciality Hospital-Dubai Investment Park, Dubai, UAE., Yurdakul OV; Department of Physical Medicine and Rehabilitation, Bezmiâlem Foundation University Faculty of Medicine, İstanbul, Türkiye., Alkan Melikoğlu M; Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Atatürk University Faculty of Medicine, Erzurum, Türkiye., Aydın Y; Department of Physical Medicine and Rehabilitation, Division of Rheumatology and Immunology, Sakarya University Faculty of Medicine, Sakarya, Türkiye., Ayhan FF; Department of Physical Medicine and Rehabilitation, Atılım University Faculty of Medicine, Ankara, Türkiye., Bodur H; Department of Physical Medicine and Rehabilitation, Yıldırım Beyazıt University Faculty of Medicine, Ankara, Türkiye., Çalış M; Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Erciyes University Faculty of Medicine, Kayseri, Türkiye., Çapkın E; Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Karadeniz Technical University Faculty of Medicine, Trabzon, Türkiye., Devrimsel G; Department of Physical Medicine and Rehabilitation, Recep Tayyip Erdoğan University Faculty of Medicine, Rize, Türkiye., Orhan K; Rheumatology Clinic, Ankara Bilkent City Hospital, Ankara, Türkiye., Hizmetli S; Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Cumhuriyet University Faculty of Medicine, Sivas, Türkiye., Kamanlı A; Department of Physical Medicine and Rehabilitation, Division of Rheumatology and Immunology, Sakarya University Faculty of Medicine, Sakarya, Türkiye., Keskin Y; Department of Physical Medicine and Rehabilitation, Bezmiâlem Foundation University Faculty of Medicine, İstanbul, Türkiye., Ecesoy H; Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Karamanoğlu Mehmetbey University, Karaman, Türkiye., Kutluk Ö; Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Akdeniz University Faculty of Medicine, Antalya, Türkiye., Şen N; Rheumatology Clinic, Kartal Dr. Lütfi Kırdar Training and Research Hospital, İstanbul, Türkiye., Faruk Şendur Ö; Department of Physical Medicine and Rehabilitation, Medicana International İzmir Hospital, İzmir, Türkiye., Tolu S; Department of Physical Medicine and Rehabilitation, Medipol University Faculty of Medicine, İstanbul, Türkiye., Toprak M; Department of Physical Medicine and Rehabilitation, Yüzüncü Yıl University Faculty of Medicine, Van, Türkiye., Tuncer T; Department of Physical Medicine and Rehabilitation, Division of Rheumatology, Akdeniz University Faculty of Medicine, Antalya, Türkiye., Nas K; Department of Physical Medicine and Rehabilitation, Division of Rheumatology and Immunology, Sakarya University Faculty of Medicine, Sakarya, Türkiye.
Jazyk:	angličtina
Zdroj:	Archives of rheumatology [Arch Rheumatol] 2024 Aug 26; Vol. 39 (3), pp. 339-349. Date of Electronic Publication: 2024 Aug 26 (Print Publication: 2024).
DOI:	10.46497/ArchRheumatol.2024.10591
Abstrakt:	Objectives: The study aimed to investigate and compare clinical features, disease activity, and the overall disease burden among psoriatic arthritis (PsA) patients across seven distinct geographic regions in Türkiye. Patients and Methods: A multicenter cross-sectional study involving 1,134 PsA patients from 25 referral centers across seven regions was conducted. Demographic and clinical characteristics, comorbidities, joint involvement, extra-articular manifestations, and disease activity measures were evaluated across regions. Results: A total of 1134 PsA patients from seven different geographic regions in Türkiye participated in this study. The highest number of participants was from the Marmara region (n=409), with subsequent representation from Central Anatolia (n=370), Aegean (n=139), Mediterranean (n=60), Black Sea (n=60), Eastern Anatolia (n=60), and Southeastern Anatolia (n=36) regions. There were significant variations in demographic profile, including age, body mass index, age of disease onset, educational status, comorbidities, and family history of both psoriasis and PsA. Clinical features, such as enthesitis, dactylitis, uveitis, and joint involvement, demonstrated significant variation across regions. Additionally, disease activity measures, including pain, patient and physician global assessments, acute phase reactants, disease activity indices, quality of life, and functional status, displayed considerable regional differences. Conclusion: This nationwide study revealed substantial regional diversity in demographic data, clinical characteristics, disease activity, and quality of life among PsA patients in Türkiye. These findings stress the need to customize treatment approaches to address regional needs and to conduct further research to uncover reasons for disparities. It is crucial to enhance region-specific approaches to improve patient care and outcomes for PsA. Competing Interests: Conflict of Interest: The authors declared no conflicts of interest with respect to the authorship and/or publication of this article. (Copyright © 2024, Turkish League Against Rheumatism.)
Databáze:	MEDLINE
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