The incidence, clinical features and outcome of urinary tract infections in geriatric patients: A prospective longitudinal study.

Autor:	Al Qahtani M; Department of Internal Medicine, Prince Sattam Bin Abdulaziz University College of Medicine, Al-Kharj, Saudi Arabia., Naghib MEDM; Department of Internal Medicine, Prince Sattam Bin Abdulaziz University College of Medicine, Al-Kharj, Saudi Arabia., Alshamrani AMM; Department of Internal Medicine, Prince Sattam Bin Abdulaziz University College of Medicine, Al-Kharj, Saudi Arabia., Al Mazroua AM; Department of Internal Medicine, Prince Sattam Bin Abdulaziz University College of Medicine, Al-Kharj, Saudi Arabia., Alayyaf ASA; Department of Internal Medicine, Prince Sattam Bin Abdulaziz University College of Medicine, Al-Kharj, Saudi Arabia., Ofisan SB; Department of Internal Medicine, Prince Sattam Bin Abdulaziz University College of Medicine, Al-Kharj, Saudi Arabia., Kamal SM; Department of Internal Medicine, Prince Sattam Bin Abdulaziz University College of Medicine, Al-Kharj, Saudi Arabia.
Jazyk:	angličtina
Zdroj:	IJID regions [IJID Reg] 2024 Oct 11; Vol. 13, pp. 100469. Date of Electronic Publication: 2024 Oct 11 (Print Publication: 2024).
DOI:	10.1016/j.ijregi.2024.100469
Abstrakt:	Objectives: This study compares the incidence, clinical features, microbial profiles, and outcomes of urinary tract infections (UTIs) in patients aged 65 years and older versus those younger than 65 years. Methods: A longitudinal cohort of 1,123 patients was divided into Group A (≥65 years, n = 560) and Group B (<65 years, n = 563) and followed for 2 years. The study analyzed UTI incidence, clinical features, microbial profiles, and outcomes, including recurrence and antibiotic resistance. Results: Over 2 years, Group A had a significantly higher UTI incidence (38.0%) compared with Group B (12.8%) ( P <0.0001). Complete recovery was less common in Group A (44.6%) than in Group B (70.83%), whereas recurrent UTIs and antibiotic resistance were more frequent in Group A (43.5% vs 22.2%, P <0.0001 and 11.7% vs 2.78%, P = 0.0017, respectively). Escherichia coli was the most prevalent pathogen in both groups, with Klebsiella and Pseudomonas species more common in recurrent UTIs, particularly in older patients. Risk factors for recurrent UTIs included advanced age, female sex, diabetes, immunosuppression, and renal stones. Conclusions: These findings highlight the need for age-specific UTI prevention and management strategies that account for microbial resistance patterns and higher recurrence rates in older patients, addressing clinical and microbial challenges. Competing Interests: The authors have no competing interests to declare. (© 2024 The Authors.)
Databáze:	MEDLINE
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