Adrenal crisis-induced cardiogenic shock (ACCS): a comprehensive review.

Autor: Heidarpour M; Isfahan Endocrine and Metabolism Research Center, Isfahan University of Medical Sciences, Isfahan, Iran., Shafie D; Heart Failure Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran., Eshraghi R; Student Research Committee, Kashan University of Medical Sciences, Kashan, Iran., Mirjalili SR; Yazd Cardiovascular Research Center, Non-Communicable Diseases Research Institute, Shahid Sadoughi University of Medical Sciences, Yazd, Iran., Bahrami A; Student Research Committee, Kashan University of Medical Sciences, Kashan, Iran., Movahed MR; University of Arizona Sarver Heart Center, Tucson, USA. rmova@aol.com.; University of Arizona College of Medicine, Phoenix, USA. rmova@aol.com.
Jazyk: angličtina
Zdroj: Heart failure reviews [Heart Fail Rev] 2025 Jan; Vol. 30 (1), pp. 227-246. Date of Electronic Publication: 2024 Nov 06.
DOI: 10.1007/s10741-024-10458-y
Abstrakt: Adrenal insufficiency (AI) is a disorder in which inadequate glucocorticoid and mineralocorticoid hormone production leads to a variety of symptoms, including fatigue, weight loss, and nausea. In some patients with unknown AI, adrenal crisis-induced cardiogenic shock (ACCS) can be the first presentation, resulting in a fatal situation. The ACCS may exhibit unresponsiveness to inotropes and fluid therapy; thus, glucocorticoid administration is the primary vital intervention, making early detection of AI essential. Hence, in this study, we review the case reports demonstrating acute cardiomyopathies in the context of AI. The review addresses the suggested underlying mechanisms, including the diminished protective effects of glucocorticoids against catecholamines in AI. We also highlighted some clues to aid physicians in considering AI as a differential diagnosis in critically ill patients presenting cardiogenic shock.
Competing Interests: Declarations. Conflict of interest: The authors declare no competing interests.
(© 2024. This is a U.S. Government work and not under copyright protection in the US; foreign copyright protection may apply.)
Databáze: MEDLINE
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