Assessing Changes in Corneal Densitometry in Patients After Small Incision Lenticule Extraction (SMILE).

Autor:	Pandya S; Ophthalmology, University of Louisville School of Medicine, Louisville, USA., Jaafar MA; Ophthalmology, University of Arizona College of Medicine - Phoenix, Phoenix, USA., Han KD; Ophthalmology, University of Arizona College of Medicine - Phoenix, Phoenix, USA., Manion GN; Ophthalmology, Creighton University School of Medicine, Omaha, USA., Moin KA; Hoopes Vision Research Center, Hoopes Vision, Draper, USA.; School of Medicine, American University of the Caribbean, Cupecoy, SXM., Zhang S; Ophthalmology, University of Arizona College of Medicine - Phoenix, Phoenix, USA., Moshirfar M; Hoopes Vision Research Center, Hoopes Vision, Draper, USA.; John A. Moran Eye Center, University of Utah School of Medicine, Salt Lake City, USA.; Eye Banking and Corneal Transplantation, Utah Lions Eye Bank, Murray, USA., Hoopes PC; Ophthalmology, Hoopes Vision, Draper, USA.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Oct 06; Vol. 16 (10), pp. e70943. Date of Electronic Publication: 2024 Oct 06 (Print Publication: 2024).
DOI:	10.7759/cureus.70943
Abstrakt:	Purpose: The aim is to assess for any lasting changes in corneal densitometry (CD) in patients who underwent small incision lenticule extraction (SMILE) and developed early transient postoperative corneal haze. Methods: This retrospective chart review analyzed 98 eyes from 49 patients who underwent SMILE at the Hoopes Vision Clinic and had one-year postoperative Pentacam CD (Oculus Optikgeräte GmbH, Wetzlar, Germany). These were compared to 78 eyes from 42 unoperated myopic control patients with documented CD measurements. The preoperative CD, measured in grayscale units (GSU), was compared between SMILE patients who developed early transient haze ("transient haze group"), SMILE patients who did not build haze ("non-haze group"), and patients who did not undergo any refractive surgery ("controls"). The postoperative CD was compared between the transient haze and non-haze groups. Then, the postoperative CD was compared to the preoperative CD for the non-haze group and transient haze group, respectively. Results: The only significant difference in preoperative CD was in the central layer of the cornea at the 6-10 mm annulus between the non-haze group and controls (17.31 ±3.77 vs. 16.18 ±3.92 GSU; p=0.04). Postoperatively, there were no differences in CD between the non-haze group and the transient haze group (p<0.05). Comparing postoperative CD to preoperative CD, the non-haze group had increased CD in the 2-6 mm annulus of the anterior (1.54 ±0.45 GSU; p=0.001), posterior (0.65 ±2.28 GSU; p=0.032), and full thickness (0.72 ±0.29 GSU; p=0.006) layers of the cornea in addition to an increased CD in the 6-10 mm annulus of the posterior corneal layer (1.19 ±0.55 GSU; p=0.049). The transient haze group had an increased CD in the 2-6 mm annulus of the anterior (2.61 ±1.09 GSU; p=0.021) and full thickness (1.44 ±0.68 GSU; p=0.039) layers of the cornea. Conclusion: There is no lasting difference in CD between patients who develop postoperative transient haze and those who do not after undergoing SMILE. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Biomedical Research Alliance of New York (BRANY) issued approval A20-12-547-823. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Pandya et al.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu