A case of pulmonary mucosa-associated lymphoid tissue lymphoma diagnosed by detecting t(11;18)(q21;q21) in bronchial lavage fluid.

Autor:	Nakamura Y; Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan., Takemasa A; Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan.; Respiratory endoscopy center, Dokkyo Medical University Hospital, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan., Ohoka Y; Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan., Tsukada N; Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan., Tsukada A; Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan., Nakazato Y; Department of Pathology, International University of Health and Welfare, 2600-1 Kitakanemaru, Otawara City, Tochigi, 324-8501, Japan., Mitani K; Department of Hematology and Oncology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan., Toyoda A; Department of Pathology, Kamitsuga General Hospital, 1-1033 Shimotamachi, Kanuma, Tochigi, 322-8550, Japan., Shimizu Y; Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan.; Respiratory endoscopy center, Dokkyo Medical University Hospital, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan., Niho S; Department of Pulmonary Medicine and Clinical Immunology, Dokkyo Medical University School of Medicine, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan.
Jazyk:	angličtina
Zdroj:	Respiratory medicine case reports [Respir Med Case Rep] 2024 Oct 17; Vol. 52, pp. 102133. Date of Electronic Publication: 2024 Oct 17 (Print Publication: 2024).
DOI:	10.1016/j.rmcr.2024.102133
Abstrakt:	A 76-year-old woman was diagnosed with mucosa-associated lymphoid tissue (MALT) lymphoma by upper gastrointestinal endoscopy. She underwent further investigation for concomitant bilateral pleural effusions and right pulmonary consolidation. MALT lymphoma with the t(11; 18)(q21; q21) translocation and API2-MALT1 were detected in pleural fluid. Lymphoma was not histopathologically diagnosed by lung biopsies, but the same translocation was identified in bronchial lavage. MALT lymphoma is often difficult to diagnose by bronchoscopy because of only mild dysplasia. However, present report on using chromosomal translocation analysis from bronchial lavage indicates that such testing may serve as a useful diagnostic adjunct in MALT lymphoma with lung involvement. Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. (© 2024 The Authors.)
Databáze:	MEDLINE
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