Gut microbiota and Parkinson's disease.
| Autor: | Wang L; Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China., Cui Y; Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China., Han B; Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China., Du Y; Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China., Salewala KS; International School, Capital Medical University, Beijing 100069, China., Wang S; Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China., Zhao W; Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China., Zhang H; Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China., Wang S; Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China., Xu X; Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China., Ma J; Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China., Zhu Y; Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China., Tuo H; Department of Neurology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Chinese medical journal [Chin Med J (Engl)] 2024 Nov 06. Date of Electronic Publication: 2024 Nov 06. |
| DOI: | 10.1097/CM9.0000000000003318 |
| Abstrakt: | Abstract: Emerging evidence suggests that dysbiosis of the gut microbiota is associated with the pathogenesis of Parkinson's disease (PD), a prevalent neurodegenerative disorder. The microbiota-gut-brain axis plays a crucial role in the development and progression of PD, and numerous studies have demonstrated the potential therapeutic benefits of modulations in the intestinal microbiota. This review provides insights into the characterization of the gut microbiota in patients with PD and highlights associations with clinical symptoms and underlying mechanisms. The discussion underscores the increased influence of the gut microbiota in the pathogenesis of PD. While the relationship is not fully elucidated, existing research demonstrates a strong correlation between changes in the composition of gut microbiota and disease development, and further investigation is warranted to explain the specific underlying mechanisms. (Copyright © 2024 The Chinese Medical Association, produced by Wolters Kluwer, Inc. under the CC-BY-NC-ND license.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|