"Oh when's your treatment ending?" "Never!" The unmet needs of cancer patients treated with immunological, biological and precision therapies: A qualitative interview study.

Autor: Crowe L; Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, United Kingdom; Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, United Kingdom., Brown MC; Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, United Kingdom; Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, United Kingdom., Lecouturier J; Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, United Kingdom., Greystoke A; Northern Centre for Cancer Care, Freeman Hospital, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, United Kingdom., Bojke A; Patient and Public Involvement, Newcastle Upon Tyne, United Kingdom., Bojke R; Patient and Public Involvement, Newcastle Upon Tyne, United Kingdom., Richardson J; Northern Centre for Cancer Care, Freeman Hospital, Newcastle Upon Tyne Hospitals NHS Foundation Trust, Newcastle Upon Tyne, United Kingdom., Wells M; Nursing Directorate, Imperial College Healthcare NHS Trust, London, United Kingdom; Department of Surgery and Cancer, Imperial College London, London, United Kingdom., Ezeala E; Department of Pharmacy, North Tyneside General Hospital, Northumbria Healthcare NHS Foundation Trust, United Kingdom., Carter L; Division of Cancer Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, United Kingdom; The Christie NHS Foundation Trust, Manchester, United Kingdom., Sharp L; Population Health Sciences Institute, Newcastle University, Newcastle Upon Tyne, United Kingdom; Newcastle University Centre for Cancer, Newcastle University, Newcastle Upon Tyne, United Kingdom., Todd A; School of Pharmacy, Newcastle University, Newcastle Upon Tyne, United Kingdom. Electronic address: adam.todd@newcastle.ac.uk.
Jazyk: angličtina
Zdroj: European journal of oncology nursing : the official journal of European Oncology Nursing Society [Eur J Oncol Nurs] 2024 Sep 23; Vol. 73, pp. 102696. Date of Electronic Publication: 2024 Sep 23.
DOI: 10.1016/j.ejon.2024.102696
Abstrakt: Purpose: To explore the unmet supportive care needs of patients with advanced cancer receiving immuno-, biological and precision (IBP) therapies.
Methods: We conducted semi-structured interviews with: (1) adults diagnosed with advanced cancer (lung, colorectal, ovary, breast, renal, melanoma) treated with an IBP therapy (e.g. tyrosine kinase inhibitors, monoclonal antibodies, immunotherapy), for at least one month; (2) healthcare professionals involved in providing hospital care for patients receiving IBP therapies. Interviews were audio-recorded, transcribed and analysed using the Framework Analysis approach; the framework comprised of 11 domains of unmet need: activities of daily living, autonomy, economic, healthcare, information, physical, psychological, role, sexual, social; and an "other" category (to capture data relating to unmet needs that did not fit within pre the-defined domains).
Results: Thirty-one patients and 22 healthcare professionals were interviewed. Ten domains of unmet needs (exceptions: spiritual, other) were evident in the data. Identified unmet needs related to: (1) utilising the IBP therapies (e.g. specific treatment side effects [physical domain], living long-term with uncertainty [psychological], others not understanding why they were not cured [social]; and (2) living with (advanced) cancer (e.g. retiring from work [role], loss of independence [autonomy]).
Conclusions: Patients with advanced cancer being treated with IBP therapies have a diverse range of often inter-related unmet needs. It is vital that healthcare professionals involved in the care of cancer patients using IBP therapies are alert to the unmet needs among this patient group. Interventions and services should be developed to address these needs.
Competing Interests: Declaration of competing interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2024 The Authors. Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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