Immunoglobulin A Nephropathy: A Review.

Autor: Aseem S; Miramonte High School , Orinda, CA, USA., Zheng S; The Permanente Medical Group , Oakland, CA, USA.; Kaiser Oakland Hospital , Oakland, CA, USA.; Division of Research, Kaiser Permanente , Oakland, CA, USA.
Jazyk: angličtina
Zdroj: The Permanente journal [Perm J] 2024 Dec 16; Vol. 28 (4), pp. 87-94. Date of Electronic Publication: 2024 Nov 05.
DOI: 10.7812/TPP/24.089
Abstrakt: Immunoglobulin A nephropathy is a primary glomerulopathy, with prevalence ranking highest in the Pacific region, followed closely by Europe, but rare in Africa. Although practice patterns likely have contributed to its prevalence, there are genetic and environmental factors that contribute as well. Management has evolved over the past decade, with recent rapid advances in diagnosis, prognosis, and therapies. This review summarizes the history, pathogenesis, and diagnosis of immunoglobulin A nephropathy and also cites relevant clinical trials, latest treatment options, and unanswered questions.
Competing Interests: Conflicts of Interest None declared
Databáze: MEDLINE