Maximal exercise capacity, peripheral muscle strength, sleep quality, and quality of life in adult patients with stable asthma.

Autor: Özdemir F; Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Çankırı Karatekin University, Çankırı, Türkiye., Boşnak Güçlü M; Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Gazi University, Ankara, Türkiye., Göktaş HE; Faculty of Health Sciences, Department of Physiotherapy and Rehabilitation, Gazi University, Ankara, Türkiye., Oğuzülgen IK; Faculty of Medicine, Department of Chest Disease, Gazi University, Ankara, Türkiye.
Jazyk: angličtina
Zdroj: The Journal of asthma : official journal of the Association for the Care of Asthma [J Asthma] 2024 Nov 12, pp. 1-13. Date of Electronic Publication: 2024 Nov 12.
DOI: 10.1080/02770903.2024.2425369
Abstrakt: Objective: The prevalence of asthma is increasing gradually worldwide. The pathophysiological process of asthma causes some alterations in the respiratory system and decreases oxygen-carbon dioxide exchange and respiration volume. These alterations may affect maximal exercise capacity, peripheral muscle strength, sleep quality, and disease-specific quality of life but have yet to be comprehensively investigated. To compare maximal exercise capacity, pulmonary function, peripheral muscle strength, dyspnea, sleep quality, and quality of life in adult patients with asthma, healthy controls were aimed.
Methods: Forty-one adult stable asthmatic patients (GINA I-III) and 41 healthy subjects were compared. Exercise capacity (cardiopulmonary exercise test [CPET]), pulmonary function (spirometry), peripheral muscle strength (dynamometer), dyspnea (modified Medical Research Council [mMRC] dyspnea scale), quality of life (Asthma Quality of Life Questionnaire [AQLQ]) and sleep quality (Pittsburgh Sleep Quality Index [PSQI]) were evaluated.
Results: Peak VO 2 , VO 2 kg, MET, VE, HR, %VE, %HR, VCO 2 parameters of CPET, FVC, FEV 1 , FEF 25-75% , and FEV 1 /FVC and quadriceps femoris, shoulder abductors, and hand grip muscle strength were significantly decreased in patients with asthma ( p  < 0.05). MMRC dyspnea scale score was increased, and AQLQ and PSQI scores decreased in asthma patients ( p  < 0.05).
Conclusions: Cardiac and pulmonary system responses to peak exercise worsened, and maximal exercise capacity and peripheral muscle strength decreased in adult patients with stable asthma. In addition, dyspnea during daily activities increases, and quality of life and sleep quality are impaired. A variety of exercise training that would benefit asthmatic patients' outcomes should be investigated.
Databáze: MEDLINE
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