Multilevel En-Bloc Excision of Thoracic Spine Primary Chondrosarcoma Through an All-Posterior Approach: A Report of Two Cases.

Autor:	Muscogliati R; Centre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR.; Hull York Medical School, University of Hull, Hull-York Medical School, Hull, GBR., Palliyil N; Centre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR., Chin DSC; Centre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR., Deogaonkar K; Centre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR., Daher M; Centre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR., Najjar E; Centre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR., Quraishi N; Centre for Spinal Studies and Surgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, GBR.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Oct 05; Vol. 16 (10), pp. e70884. Date of Electronic Publication: 2024 Oct 05 (Print Publication: 2024).
DOI:	10.7759/cureus.70884
Abstrakt:	Chondrosarcomas are malignant, cartilage-forming neoplasms. As these tumours are resistant to chemotherapy and radiotherapy, en-bloc excision of the tumour with wide margins is the only option that provides maximum disease-free survival and possible cure. We present two cases of primary chondrosarcoma of the thoracic spine treated by multilevel en-bloc excision through an all-posterior approach. Case 1 describes a 48-year-old female who presented with mid-back pain for six months. MRI revealed an expansile lesion between T9 and T11; a biopsy confirmed this to be chondrosarcoma. Following a posterior-only approach, the entire tumour mass with the overlying pleura, part of the T9-T11 vertebral body and the posterior elements, as well as the posteromedial part of the ninth, tenth, and eleventh ribs, were removed en bloc. Case 2 describes a 29-year-old male who presented with mid-back pain for five months. MRI revealed a lesion at T10, which was later confirmed on histopathological examination to be chondrosarcoma, affecting T9-T11. Using a posterior-only approach, the entire tumour mass, with part of T8-T11 was delivered en bloc. Both patients made an uneventful recovery, and there were no signs of disease at 24 months post-operatively. Despite being technically demanding, multilevel en-bloc tumour resection of the spine remains the mainstay in certain primary tumours, as it is potentially curative. Although the overall complication percentage following multilevel en-bloc resections was high, the local recurrence rate was significantly low. While most published articles recommend a posterior-only approach for limited disease, the cases in this report suggest that a posterior-only approach could also be viable for select cases of multilevel chondrosarcoma. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Muscogliati et al.)
Databáze:	MEDLINE
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