Clinical profile of patients with acute traumatic brain injury undergoing cranial surgery in the United States: report from the 18-centre TRACK-TBI cohort study.

Autor:	Yue JK; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., Kanter JH; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., Barber JK; Departments of Neurological Surgery and Biostatistics, University of Washington, Seattle, WA, United States., Huang MC; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., van Essen TA; University Neurosurgical Center Holland, Leiden University Medical Center, Haaglanden Medical Center, HAGA, Leiden, The Hague, the Netherlands.; Department of Surgery, Division of Neurosurgery, QEII Health Sciences Centre and Dalhousie University, Halifax, Nova Scotia, Canada., Elguindy MM; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., Foreman B; Department of Neurology, University of Cincinnati, Cincinnati, OH, United States., Korley FK; Department of Emergency Medicine, University of Michigan, Ann Arbor, MI, United States., Belton PJ; Department of Neurological Surgery, University of Wisconsin-Madison, Madison, WI, United States., Pisică D; Center for Medical Decision Making, Department of Epidemiology and Public Health, Erasmus MC, University Center Rotterdam, Rotterdam, the Netherlands.; Department of Neurosurgery, Erasmus MC - University Medical Center Rotterdam, Rotterdam, the Netherlands., Lee YM; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., Kitagawa RS; Department of Neurological Surgery, The University of Texas Health Science Center at Houston, Houston, TX, United States., Vassar MJ; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., Sun X; Biostatistics Research Center, Herbert Wertheim School of Public Health and Longevity Science, University of California San Diego, La Jolla, CA, United States., Satris GG; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., Wong JC; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., Ferguson AR; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., Huie JR; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., Wang KKW; Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, United States., Deng H; Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States., Wang VY; Department of Neurological Surgery, University of Texas at Austin, Austin, TX, United States., Bodien YG; Department of Neurology, Harvard Medical School, Boston, MA, United States., Taylor SR; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., Madhok DY; Departments of Emergency Medicine and Neurology, University of California, San Francisco, San Francisco, CA, United States., McCrea MA; Department of Neurological Surgery, Medical College of Wisconsin, Milwaukee, WI, United States., Ngwenya LB; Department of Neurological Surgery, University of Cincinnati, Cincinnati, OH, United States., DiGiorgio AM; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., Tarapore PE; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., Stein MB; Department of Psychiatry, University of California, San Diego, La Jolla, CA, United States., Puccio AM; Department of Neurobiology, Morehouse School of Medicine, Atlanta, GA, United States., Giacino JT; Department of Rehabilitation Medicine, Spaulding Rehabilitation Center, Boston, MA, United States., Diaz-Arrastia R; Department of Neurology, University of Pennsylvania, Philadelphia, PA, United States., Lingsma HF; Center for Medical Decision Making, Department of Epidemiology and Public Health, Erasmus MC, University Center Rotterdam, Rotterdam, the Netherlands., Mukherjee P; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States.; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States., Yuh EL; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States.; Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA, United States., Robertson CS; Department of Neurological Surgery, Baylor College of Medicine, Houston, TX, United States., Menon DK; Division of Anaesthesia, Department of Medicine, University of Cambridge, Cambridge, United Kingdom., Maas AIR; Department of Neurological Surgery, Antwerp University Hospital, Edegem, Belgium.; Department of Translational Neuroscience, University of Antwerp, Antwerp, Belgium., Markowitz AJ; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States., Jain S; Biostatistics Research Center, Herbert Wertheim School of Public Health and Longevity Science, University of California San Diego, La Jolla, CA, United States., Okonkwo DO; Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, United States., Temkin NR; Departments of Neurological Surgery and Biostatistics, University of Washington, Seattle, WA, United States., Manley GT; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, United States.; Brain and Spinal Injury Center, Zuckerberg San Francisco General Hospital, San Francisco, CA, United States.
Jazyk:	angličtina
Zdroj:	Lancet regional health. Americas [Lancet Reg Health Am] 2024 Oct 17; Vol. 39, pp. 100915. Date of Electronic Publication: 2024 Oct 17 (Print Publication: 2024).
DOI:	10.1016/j.lana.2024.100915
Abstrakt:	Background: Contemporary surgical practices for traumatic brain injury (TBI) remain unclear. We describe the clinical profile of an 18-centre US TBI cohort with cranial surgery. Methods: The prospective, observational Transforming Research and Clinical Knowledge in Traumatic Brain Injury Study (2014-2018; ClinicalTrials.gov #NCT02119182) enrolled subjects who presented to trauma centre and received head computed tomography within 24-h (h) post-TBI. We performed a secondary data analysis in subjects aged ≥17-years with hospitalisation. Clinical characteristics, surgery type/timing, hospital and six-month outcomes were reported. Findings: Of 2032 subjects (age: mean = 41.4-years, range = 17-89-years; male = 71% female = 29%), 260 underwent cranial surgery, comprising 65% decompressive craniectomy, 23% craniotomy, 12% other surgery. Subjects with surgery (vs. without surgery) presented with worse neurological injury (median Glasgow Coma Scale = 6 vs. 15; midline shift ≥5 mm: 48% vs. 2%; cisternal effacement: 61% vs. 4%; p < 0.0001). Median time-to-craniectomy/craniotomy was 1.8 h (interquartile range = 1.1-5.0 h), and 67% underwent intracranial pressure monitoring. Seventy-three percent of subjects with decompressive craniectomy and 58% of subjects with craniotomy had ≥3 intracranial lesion types. Decompressive craniectomy (vs. craniotomy) was associated with intracranial injury severity (median Rotterdam Score = 4 vs. 3, p < 0.0001), intensive care length of stay (median = 13 vs. 4-days, p = 0.0002), and six-month unfavourable outcome (62% vs. 30%; p = 0.0001). Earlier time-to-craniectomy was associated with intracranial injury severity. Interpretation: In a large representative cohort of patients hospitalised with TBI, surgical decision-making and time-to-surgery aligned with intracranial injury severity. Multifocal TBIs predominated in patients with cranial surgery. These findings summarise current TBI surgical practice across US trauma centres and provide the foundation for analyses in targeted subpopulations. Funding: National Institute of Neurological Disorders and Stroke; US Department of Defense; Neurosurgery Research and Education Foundation. Competing Interests: AMD declares: grant funding from the Mercatus Center at George Mason University (not related to the current work). DKM declares: grant funding from United Kingdom National Institute for Health Research (not related to the current work). KKWW declares: is a shareholder of Gryphon Bio, Inc. (not related to the current work). All other authors declare no conflict of interest. (© 2024 The Author(s).)
Databáze:	MEDLINE
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