Impact of fast-track on recurrence and malignant transformation of patients with inverted papilloma.

Autor:	Gydesen K; Department of Otorhinolaryngology, Head & Neck Surgery and Audiology, Rigshospitalet and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Bülow R; Department of Otorhinolaryngology, Head & Neck Surgery and Audiology, Rigshospitalet and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Aanaes K; Department of Otorhinolaryngology, Head & Neck Surgery and Audiology, Rigshospitalet and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Lomholt AF; Department of Otorhinolaryngology, Head & Neck Surgery and Audiology, Rigshospitalet and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Agander T; Department of Pathology, Rigshospitalet and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., von Buchwald C; Department of Otorhinolaryngology, Head & Neck Surgery and Audiology, Rigshospitalet and Faculty of Health and Medical Sciences, University of Copenhagen, Denmark., Sjöstedt S; Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Denmark.
Jazyk:	angličtina
Zdroj:	Acta oto-laryngologica [Acta Otolaryngol] 2024 Nov-Dec; Vol. 144 (11-12), pp. 631-634. Date of Electronic Publication: 2024 Nov 04.
DOI:	10.1080/00016489.2024.2408741
Abstrakt:	Background: Inverted papilloma is a benign epithelial tumour located in the sinonasal tract with a high recurrence rate and a potential of malignant transformation. From 2017, patients with IP were included in our fast-track regime similar to head and neck cancer patients, including follow-up at 2, 6, 12, 18 and 24 months after surgery, then yearly for a total of 5 years. Aims/objectives: This study aims to compare the recurrence rate and malignant transformation of patients with IP treated at a university centre following the implementation of a fast-track regime including a close follow-up. Methods: A retrospective study was performed on all patients with IP diagnosed between 2018 and 2022. Results: The study included 125 patients, all surgically treated for IP. Eight patients (6%) also presented with SCC at the time of diagnosis. The recurrence rate of benign IP was 17%. Most tumours originated in the maxillary sinus (48/117, 41%). No cases of metachronous cancer were seen during the follow-up. Conclusions and Significance: The majority of recurrences (90%) occurred within the first 2 years after treatment. No cases of malignant transformation were seen in the follow-up period. The rigorous follow-up program potentially contributed to the detection of recurrence before malignant transformation.
Databáze:	MEDLINE
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