Acute Fluoride Toxicity Due to Intentional Ingestion of Hydrofluoric Acid Commercial Product.
| Autor: | Macias T; From the Washoe County Regional Medical Examiner's Office, Reno, NV., Bingham Abujasen K; University of Utah and ARUP Laboratories, Department of Pathology, Salt Lake City, UT., Usera PC, Knight LD |
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| Jazyk: | angličtina |
| Zdroj: | The American journal of forensic medicine and pathology [Am J Forensic Med Pathol] 2024 Dec 01; Vol. 45 (4), pp. 331-334. Date of Electronic Publication: 2024 Oct 29. |
| DOI: | 10.1097/PAF.0000000000000948 |
| Abstrakt: | Abstract: Hydrofluoric (HF) acid, an irritating and corrosive acid, is commonly found in cleaning supplies. Fatal HF acid ingestion has been documented, although relatively rare. We report a case of acute fluoride toxicity suicide due to the ingestion of a commercial product containing HF acid and ammonium bifluoride. To our knowledge, this is the first to describe the associated gastrointestinal histopathology in detail.A 56-year-old woman was found deceased near a rust remover product and a notebook containing suicide methods via chemical ingestion. Gross autopsy findings included laryngeal mucosal petechial hemorrhages; patchy esophageal mucosal denudation; and autolyzed, red-black discolored gastric mucosa. Histology of the esophagus demonstrated superficial mucosal ulceration with necrosis of the squamous mucosa, vascular congestion, and lymphoid aggregates in the lamina propria; muscularis mucosae and muscularis propria were unperturbed. The stomach showed superficial coagulative necrosis of the oxyntic crypts, with fresh microhemorrhage dissecting the glandular mucosa away from the muscularis mucosae; muscularis mucosae, submucosa, muscularis propria, and serosa were all spared.Toxicology revealed an elevated fluoride ion concentration (20 mg/L). Death was attributed to acute fluoride toxicity due to intentional ingestion of a commercial product containing HF acid and ammonium bifluoride, and the manner was suicide. Competing Interests: The authors report no conflict of interest. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.) |
| Databáze: | MEDLINE |
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