Sleep and perivascular disruption: An illustrative case of severe sleep apnea, an enlarged Virchow-Robin space, and contralateral asymmetric periodic limb movements.

Autor: Adirim ZL; Department of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada. Electronic address: zachary.adirim@yale.edu., Heyn C; Division of Neuroradiology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada., Murray BJ; Division of Neurology, Department of Medicine, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.
Jazyk: angličtina
Zdroj: Sleep medicine [Sleep Med] 2023 Oct 24; Vol. 112, pp. 191-193. Date of Electronic Publication: 2023 Oct 24.
DOI: 10.1016/j.sleep.2023.10.026
Abstrakt: Virchow-Robin spaces (VRS) are perivascular spaces that have been associated with impaired glymphatic function, poor sleep quality and sleep disorders. These spaces are also associated with neurological impairment. We report a case of a young adult male who presented with severe untreated sleep apnea, shift-work disorder, and excessive asymmetric periodic limb movements disorder in association with a prominent radiologically-identified VRS in the contralateral basal ganglia. This case illustrates the complex "chicken and egg" association between impaired sleep, the development of VRS, and subsequent sleep disorder most likely attributable to the development of this perivascular abnormality.
Competing Interests: Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2023 Elsevier B.V. All rights reserved.)
Databáze: MEDLINE