Transcutaneous neurostimulation parameters for neuropathic radicular pain: Results from a two period crossover randomized trial.

Autor: Ducoulombier V; Department of Rheumatology, Saint-Philibert Hospital, Catholic University of Lille, Lomme, France. Electronic address: ducoulombier.vincent@ghicl.net., Challi H; Department of Algology, Béthune Hospital Center, Béthune, France., Petit P; Department of Algology, Saint-Vincent Hospital, Catholic University of Lille, Lille, France., Leroy B; Department of Algology, Roubaix Hospital Center, Roubaix, France., Versavel A; Department of Algology, Saint-Vincent Hospital, Catholic University of Lille, Lille, France., Luraschi H; Department of Rheumatology, Saint-Philibert Hospital, Catholic University of Lille, Lomme, France., Chiquet R; Department of Algology, Saint-Vincent Hospital, Catholic University of Lille, Lille, France., Zenati K; Department of Algology, Béthune Hospital Center, Béthune, France., Budzik JF; Department of Radiology, Saint-Philibert Hospital, Catholic University of Lille, Lomme, France., Desrousseaux JF; Department of Orthopedic Surgery, Saint-Philibert Hospital, Catholic University of Lille, Lomme, France., Khenioui H; Department of Reeducation, Saint-Philibert Hospital, Catholic University of Lille, Lomme, France., Bera-Louville A; Department of Rheumatology, Roger-Salengro Hospital, Lille, France., Houvenagel E; Department of Rheumatology, Saint-Philibert Hospital, Catholic University of Lille, Lomme, France., Norberciak L; Research Department - Biostatistics and Methodology, Catholic University of Lille, Lomme, France., Pascart T; Department of Rheumatology, Saint-Philibert Hospital, Catholic University of Lille, Lomme, France.
Jazyk: angličtina
Zdroj: Joint bone spine [Joint Bone Spine] 2024 Oct 26; Vol. 92 (2), pp. 105797. Date of Electronic Publication: 2024 Oct 26.
DOI: 10.1016/j.jbspin.2024.105797
Abstrakt: Objectives: Transcutaneous neurostimulation (TENS) is commonly used in the treatment of chronic radicular pain, but without any consensus on the type of current to be delivered. The aim of this study was to compare the conventional high-frequency, low-intensity current called c-TENS with a mixed current called m-TENS, combining c-TENS with a low-frequency, high-intensity current.
Methods: This was a single-blind, two-period crossover randomized trial. Included patients had chronic (≥3months), neuropathic (dn4≥4) radicular pain of at least moderate intensity (Visual Analogic Scale [VAS]≥40mm [0-100mm]). Patients were randomized to receive either c-TENS or m-TENS first, then the other, and both during one month. The primary outcome was the level of radicular pain, measured by VAS at the end of each of the two period.
Results: Seventy-four patients were included (mean age: 51.9±13.5years, female proportion: 65.6%). The mean duration of radicular pain was 45.2±51months and the mean radicular intensity was 67±12.5/100mm. After one month of treatment, VAS decreased to 53.9±20.1mm under c-TENS and to 53.9±21.3 under m-TENS (NS). Thirteen patients (20.3%) had a VAS<40/100 with either c-TENS or m-TENS (NS). Tolerance was the same for the two modes. Twenty-nine patients (46%) designated c-TENS as the most effective mode, and 34 patients (54%) designated m-TENS.
Conclusion: This study shows no difference in terms of efficacy or tolerance between c-TENS and m-TENS. There is no justification for preferring one of these two modes over the other for the treatment of chronic neuropathic radicular pain.
Competing Interests: Disclosure of interest The authors declare that they have no competing interest.
(Copyright © 2024 The Authors. Published by Elsevier Masson SAS.. All rights reserved.)
Databáze: MEDLINE
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