| Autor: |
Hadroug A; Department of Chemistry, Med Boudiaf University, M'sila, Algeria.; Laboratory of Applied Microbiology, Faculty of Life and Natural Sciences, Ferhat Abbas Setif1University, Setif, Algeria., Zengin G; Department of Biology, Faculty of Science, Selcuk University, Konya, Turkey., Belhattab R; Laboratory of Applied Microbiology, Faculty of Life and Natural Sciences, Ferhat Abbas Setif1University, Setif, Algeria., Cakmak YS; Department of Biotechnology and Molecular Biology, Faculty of Science and Letters, Aksaray University, Aksaray, Turkey., Rebbas K; Department of Life and Natural Sciences, Med Boudiaf University, M'sila, Algeria. |
| Jazyk: |
angličtina |
| Zdroj: |
Natural product research [Nat Prod Res] 2024 Nov 02, pp. 1-8. Date of Electronic Publication: 2024 Nov 02. |
| DOI: |
10.1080/14786419.2024.2419498 |
| Abstrakt: |
This research explored the impact of methanolic extracts from the fruits and leaves of Ilex aquifolium L., a rare Algerian species, on several enzymes, focusing on tyrosinase, α-amylase, α-glucosidase, and cholinesterases, as well as their antioxidant potential in vitro assays, including phosphomolybdenum, DPPH, ABTS, CUPRAC, FRAP, and MCA. HPLC-DAD analysis identified chlorogenic acid, rosmarinic acid, hesperidin, and quercetin as predominant phenolic components. Both extracts exhibited notable antioxidant properties, up to 250.08 mg TE/g for fruits and 237.08 mg TE/g for leaf extracts. Enzyme inhibitory assays demonstrated significant inhibition against AChE and BChE with maximum activities of 2.34 mg GALAE/g in leaves and 4.32 mg GALAE/g in fruits. Additionally, considerable tyrosinase inhibition was observed in leaves at 39.69 mg KAE/g. These findings highlight I. aquifolium L. as a valuable source for investigating natural antioxidants and enzyme inhibitors, particularly for possible cosmetics and food additives applications. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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