| Autor: |
Fokkens WJ; Department of Otorhinolarynogology and head/neck surgery, Amsterdam University Medical Centres, Amsterdam, The Netherlands., Sedaghat AR; Department of Otolaryngology - Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, OH, USA., Soyka MB; Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital Zurich, University of Zurich, Zurich, Switzerland; Faculty of Medicine, University of Zurich, Zurich, Switzerland., Reitsma S; Department of Otorhinolarynogology and head/neck surgery, Amsterdam University Medical Centres, Amsterdam, The Netherlands. |
| Abstrakt: |
This review discusses major developments in chronic rhinosinusitis. The latest papers on prevalence of the disease, the burden for patients and society, the lack of awareness, the development of patient classifications and the consequences for the management of the disease. Our discussion includes major developments in the treatment of the disease with biologics but also their limitations. Recent developments also include evolution in the goals of care, where until recently we were content with control of disease but now start to aim for remission and maybe even cure. To reach that aim we need better definitions of disease, outcomes and biomarkers to predict the optimal moment of intervention in the development of the disease. Time will tell whether earlier intervention can prevent development of the disease and later sequelae. |
