Neural Stimulation of Brain Organoids with Dynamic Patterns: A Sentiomics Approach Directed to Regenerative Neuromedicine.
| Autor: | Pereira A Jr; Philosophy Graduate Program, UNESP/Marilia Campus, São Paulo State University, Botucatu 18618-689, Brazil., Garcia JW; Architecture and Urbanism, USP and PUC, São Paulo, Brazil.; Media Lab, MIT, Cambridge, MA, USA., Muotri A; Stem Cell Program, Department of Pediatrics & Cellular Molecular Medicine/UCSD, Institute for Genomic Medicine, San Diego, CA, USA. |
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| Jazyk: | angličtina |
| Zdroj: | NeuroSci [NeuroSci] 2023 Jan 16; Vol. 4 (1), pp. 31-42. Date of Electronic Publication: 2023 Jan 16 (Print Publication: 2023). |
| DOI: | 10.3390/neurosci4010004 |
| Abstrakt: | The new science called Sentiomics aims to identify the dynamic patterns that endow living systems with the capacity to feel and become conscious. One of the most promising fields of investigation in Sentiomics is the development and 'education' of human brain organoids to become sentient and useful for the promotion of human health in the (also new) field of Regenerative Neuromedicine. Here, we discuss the type of informational-rich input necessary to make a brain organoid sentient in experimental settings. Combining this research with the ecological preoccupation of preserving ways of sentience in the Amazon Rainforest, we also envisage the development of a new generation of biosensors to capture dynamic patterns from the forest, and use them in the 'education' of brain organoids to afford them a 'mental health' quality that is likely to be important in future advances in 'post-humanist' procedures in regenerative medicine. This study is closely related to the psychophysical approach to human mental health therapy, in which we have proposed the use of dynamic patterns in electric and magnetic brain stimulation protocols, addressing electrochemical waves in neuro-astroglial networks. Competing Interests: Conflicts of InterestThe authors declare no conflict of interest. (© 2023 by the authors.) |
| Databáze: | MEDLINE |
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