Consensus Agreements on Regenerative Aesthetics: A Focus on Regenerative Biostimulation With Calcium Hydroxylapatite.
Autor: | Goldie K; Kate Goldie, Clinic 77, London, United Kingdom., Chernoff G; Chernoff Cosmetic Surgery, Indianapolis, Indiana., Corduff N; River End Aesthetics, Geelong, Australia., Davies O; School of Sport Exercise and Health Sciences, Loughborough University, Leicestershire, United Kingdom., van Loghem J; UMA, Amsterdam, Netherlands., Viscomi B; B Viscomi Dermatology, São Paulo, Brazil. |
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Jazyk: | angličtina |
Zdroj: | Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] [Dermatol Surg] 2024 Nov 01; Vol. 50 (11S), pp. S172-S176. Date of Electronic Publication: 2024 Oct 10. |
DOI: | 10.1097/DSS.0000000000004437 |
Abstrakt: | Background: A growing population of patients is seeking treatments that not only affect their overlying features but also restore a more biologically youthful structure and function to the underlying tissue. These strategies are part of what is known as regenerative aesthetics (RA). As an emergent field, clarity regarding the precise definitions and aims of RA and methods to measure the regenerative capacity of RA treatments are lacking. Methods: A panel of 6 multidisciplinary experts discussed the foundational aspects of RA. Consensus statements covered aspects of RA including terminology, goals of treatment, treatment strategies, and biological benchmarks indicating regeneration. Consensus on a statement was defined as ≥75% agreement. Results: Panelists emphasized the importance of natural, youthful tissue architecture and function including cellular and extracellular components. Replacement of a single biological component was not considered sufficient for an aesthetic treatment to be described as regenerative. Rather, the relative amounts, ratios, types, and organization are important to determine regenerative potential. Calcium hydroxylapatite is an example of an aesthetic injectable with evidence of regenerative capacity, as demonstrated by its ability to improve collagen type I/III ratios as well as induce the production of elastin and proteoglycans, which ultimately improve measures of skin quality. (Copyright © 2024 by the American Society for Dermatologic Surgery, Inc. Published by Wolters Kluwer Health, Inc. All rights reserved.) |
Databáze: | MEDLINE |
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