The Association between Blood Pressure and Clinical Outcomes in Patients Undergoing Transcatheter Aortic Valve Implantation.

Autor:	Goldberg I; Department of Internal Medicine F - Recanati, Beilinson Hospital, Rabin Medical Centre, Petah Tikva, Israel.; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.; Institute of Hematology, Davidoff Cancer Centre, Rabin Medical Centre, Petah Tikva, Israel., Landes U; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.; Department of Cardiology, Edith Wolfson Medical Center, Holon, Israel., Drozdinsky G; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.; Infectious Diseases Unit, Rabin Medical Center, Tel Aviv, Israel., Codner P; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.; Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel., Bental T; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.; Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel., Orvin K; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.; Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel., Schamroth Pravda N; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.; Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel., Goldberg L; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.; Department of Pediatrics B, Schneider Children's Medical Center of Israel, Petah Tikva, Israel., Soudry O; Department of Internal Medicine F - Recanati, Beilinson Hospital, Rabin Medical Centre, Petah Tikva, Israel.; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel., Lerman TT; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.; Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel., Kornowski R; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.; Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel., Eisen A; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.; Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel., Vaknin-Assa H; School of Medicine, Faculty of Medical and Health Sciences, Tel Aviv University, Tel Aviv, Israel.; Department of Cardiology, Rabin Medical Center, Petah Tikva, Israel.
Jazyk:	angličtina
Zdroj:	Pulse (Basel, Switzerland) [Pulse (Basel)] 2024 Jul 22; Vol. 12 (1), pp. 85-94. Date of Electronic Publication: 2024 Jul 22 (Print Publication: 2024).
DOI:	10.1159/000540209
Abstrakt:	Introduction: Transcatheter aortic valve implantation (TAVI) has emerged as a common and effective treatment for patients with severe aortic stenosis. Changes in systemic blood pressure after TAVI have been described, yet their prognostic value is not established. Thus, we aimed to examine the association of the periprocedural changes in systolic blood pressure (SBP) and in pulse pressure on clinical outcomes after the procedure. Methods: A retrospective study of consecutive patients who underwent TAVI procedure in our medical center. We assessed the effect of the periprocedural changes in blood pressure measurements on mortality, acute myocardial infarction, stroke and hospitalizations at 1 year and on the combined outcome of death, myocardial infarction, and stroke 1 year following the procedure. Results: Our cohort included 455 patients (44% males). Of them, 343 patients (75.4%) had raised SBP immediately after the procedure. Patients with raised SBP had a significantly higher rate of the 1-year composite outcome, compared to patients who did not have a raise in SBP following the procedure (43 [13%] vs. 6 [5.4%], respectively, p = 0.033). After adjustment for age and sex, the postprocedural increase in SBP was significantly associated with the composite outcome, with a hazard ratio of 2.42, 95% CI: 1.03-5.7. Conclusion: An immediate increase in SBP after TAVI is associated with worse 1-year clinical cardiovascular outcomes. Competing Interests: The authors have no conflicts of interest to declare. (© 2024 The Author(s). Published by S. Karger AG, Basel.)
Databáze:	MEDLINE
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