Treatment Planning Comparison of Gantry-based and Fixed Beams for the Treatment of Liver Tumors With Carbon Ion Therapy.

Autor:	Miyasaka Y; Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan; yuya.aoba@gmail.com., Lee SH; Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan., Souda H; Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan., Kaneko T; Department of Radiology, Yamagata University Faculty of Medicine, Yamagata, Japan., Hagiwara Y; Department of Radiology, Yamagata University Faculty of Medicine, Yamagata, Japan., Chai H; Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan., Ishizawa M; Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan., Sato H; Department of Radiology, Yamagata University Faculty of Medicine, Yamagata, Japan., Iwai T; Department of Heavy Particle Medical Science, Yamagata University Graduate School of Medical Science, Yamagata, Japan.
Jazyk:	angličtina
Zdroj:	In vivo (Athens, Greece) [In Vivo] 2024 Nov-Dec; Vol. 38 (6), pp. 3002-3010.
DOI:	10.21873/invivo.13783
Abstrakt:	Background/aim: This study aimed to compare the use of a rotating gantry in liver tumor carbon-ion radiotherapy using of a fixed-port for treatment planning. Materials and Methods: Thirty patients with liver tumors were analyzed. Three treatment plans were developed for each case: one with a rotating gantry with a 360° angle, one with fixed ports of 0° and 90° with a ±20° couch rolling setting, and one with fixed ports of 45° and 90° with a ±20° couch rolling setting. The dose-volume histogram parameters of the clinical target volume (CTV) and organs at risk (OARs) for each treatment plan were compared. Results: Significant differences in the volume of the liver-gross tumor volume (GTV) of normal liver irradiated with 5 Gy to 15 Gy were found between the gantry treatment plans and fixed-port treatment plans. There were no significant differences in the OARs, except for the CTV and liver GTV, between the gantry and fixed-port treatment plans. Conclusion: The study results support the potential of using a rotating gantry to reduce liver doses, especially in the low-to-medium dose range, while maintaining target and OAR doses except for the liver. A rotating gantry could be especially useful in cases in which the relationship between the tumor and OAR is complicated by location. (Copyright © 2024, International Institute of Anticancer Research (Dr. George J. Delinasios), All rights reserved.)
Databáze:	MEDLINE
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