Impact of smoke-free legislation on stroke risk: A systematic review and meta-analysis.

Autor:	Chua ZX; Lee Kong Chian School of Medicine, Nanyang Technology University, Singapore., Yeh Lai Amanda C; Duke-NUS Medical School, Singapore., Lam TJR; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Ong JSP; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Lim SYW; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Kumar S; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Lim MJR; Division of Neurosurgery, Department of Surgery, National University Hospital, Singapore., Tan BYQ; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Division of Neurosurgery, Department of Surgery, National University Hospital, Singapore., Aik J; Environmental Epidemiology and Toxicology Division, National Environment Agency, Singapore.; Pre-hospital and Emergency Research Centre, Duke-NUS Medical School, Singapore., Ho AFW; Pre-hospital and Emergency Research Centre, Duke-NUS Medical School, Singapore.; Department of Emergency Medicine, Singapore General Hospital, Singapore.; Singapore Centre for Population Health Research and Implementation, SingHealth Regional Health System, Singapore.
Jazyk:	angličtina
Zdroj:	European stroke journal [Eur Stroke J] 2024 Oct 30, pp. 23969873241293566. Date of Electronic Publication: 2024 Oct 30.
DOI:	10.1177/23969873241293566
Abstrakt:	Purpose: Secondhand smoke significantly increases the risk of cerebrovascular diseases, prompting recent public smoking bans. We aimed to ascertain the effects of smoke-free legislation on stroke incidence and mortality. Methods: We systematically searched Medline, Embase, Cochrane Library, and Scopus up to August 13, 2023, for studies reporting changes in stroke incidence following partial or comprehensive smoking bans. A random-effects meta-analysis was conducted on hospital admissions and mortality for stroke, stratified based on comprehensiveness of the ban ((i) workplaces-only, (ii) workplaces and restaurants, (iii) workplaces, restaurants and bars). The effect of post-ban follow-up duration was assessed visually by a forest plot, while meta-regression was employed to evaluate for any dose-response relationship between ban comprehensiveness and stroke risk. Findings: Of 3987 records identified, 15 studies analysing bans across a median follow-up time of 24 months (range: 3-67) were included. WRB bans were associated with reductions in the rates of hospital admissions for stroke (nine studies; RR, 0.918; 95% CI, 0.872-0.967) and stroke mortality (three studies; RR, 0.987; 95% CI, 0.952-1.022), although the latter did not reach statistical significance. There was no significant difference in the risk of stroke admissions for studies with increased ban comprehensiveness and no minimum duration for significant post-ban effects to be observed. Discussion and Conclusion: Legislative smoking bans were associated with significant reductions in stroke-related hospital admissions, providing evidence for its utility as a public health intervention. Competing Interests: Declaration of conflicting interestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze:	MEDLINE
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