TB or Not TB, That is the Question?

Autor: McAuliffe E; Acute Medical Unit, Galway University Hospital, Galway, Ireland., Renton B; Acute Medical Unit, Galway University Hospital, Galway, Ireland.
Jazyk: angličtina
Zdroj: British journal of hospital medicine (London, England : 2005) [Br J Hosp Med (Lond)] 2024 Oct 30; Vol. 85 (10), pp. 1-7. Date of Electronic Publication: 2024 Oct 27.
DOI: 10.12968/hmed.2024.0180
Abstrakt: A 26-year-old female presented with a 3-month history of dry cough, unintentional weight loss, night sweats and fatigue. Her background history was significant for ulcerative colitis, managed with Adalimumab for almost 2 years. Clinical examination was unremarkable, apart from some mild pallor. Abnormal chest x-ray findings prompted a computerised tomography (CT) thorax which demonstrated multifocal peri-bronchial consolidation. The differential diagnosis was multifocal organising pneumonia and tuberculosis (TB). Extensive investigations, including invasive bronchial imaging and biopsy, ultimately ruled out TB. This paper reports a case of Adalimumab-induced organising pneumonia and discusses its clinical implications.
Databáze: MEDLINE