Treatment of Latent Tuberculosis Infection in a Kawasaki Disease Patient Receiving Anti-Tumor Necrosis Factor Alpha (TNFα) Therapy.

Autor: Yokoyama K; Pediatrics, Japanese Red Cross Wakayama Medical Center, Wakayama, JPN., Yakuo T; Pediatrics, Japanese Red Cross Wakayama Medical Center, Wakayama, JPN., Mamada M; Pediatrics, Japanese Red Cross Wakayama Medical Center, Wakayama, JPN.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2024 Sep 28; Vol. 16 (9), pp. e70407. Date of Electronic Publication: 2024 Sep 28 (Print Publication: 2024).
DOI: 10.7759/cureus.70407
Abstrakt: Kawasaki disease (KD) is a common vasculitis syndrome that mainly affects children. Latent tuberculosis infection (LTBI) is a tuberculosis (TB) infection without signs or symptoms. Here, we report the case of a boy who traveled from abroad, was diagnosed with KD at our hospital, and underwent multidisciplinary treatment, including anti-TNFα therapy. Subsequently, the patient was found to have LTBI and was administered anti-TB treatment. To the best of our knowledge, this is the first reported case of LTBI in a KD patient receiving immunosuppressive therapy containing anti-TNFα.
Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Ethics Committee in Japanese Red Cross Wakayama Medical Centre issued approval 1180. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work.
(Copyright © 2024, Yokoyama et al.)
Databáze: MEDLINE
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