Evaluation of arterial spin labeling in the diagnosis and monitoring of myelin oligodendrocyte glycoprotein-associated cerebral cortical encephalitis.

Autor: Shibahara T; Department of Neurology, National Hospital Organization Fukuokahigashi Medical Center, Koga, Japan., Yamanaka K; Department of Neurology, National Hospital Organization Fukuokahigashi Medical Center, Koga, Japan., Matsuoka M; Department of Neurology, National Hospital Organization Fukuokahigashi Medical Center, Koga, Japan., Tachibana M; Department of Neurology, National Hospital Organization Fukuokahigashi Medical Center, Koga, Japan., Kuroda J; Department of Neurology, National Hospital Organization Fukuokahigashi Medical Center, Koga, Japan., Nakane H; Department of Neurology, National Hospital Organization Fukuokahigashi Medical Center, Koga, Japan.
Jazyk: angličtina
Zdroj: Multiple sclerosis (Houndmills, Basingstoke, England) [Mult Scler] 2024 Oct 29, pp. 13524585241291444. Date of Electronic Publication: 2024 Oct 29.
DOI: 10.1177/13524585241291444
Abstrakt: Myelin oligodendrocyte glycoprotein (MOG)-associated disorders are inflammatory demyelinating diseases of the CNS. Cerebral cortical encephalitis (CCE) is characterized by cortical fluid-attenuated inversion recovery hyperintensity with seizures and headaches. We report two cases of MOG antibody-associated CCE (MOG-CCE) evaluated using serial MRI sequences, including arterial spin labeling (ASL), pre- and posttreatment. In both patients, ASL demonstrated hyperperfusion correlating with disease activity, which normalized following steroid therapy. Our cases highlight the usefulness of ASL in early detection, monitoring, and assessment of treatment response in MOG-CCE.
Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
Databáze: MEDLINE