Facilitators and barriers to maternal immunization and strategies to improve uptake in low-income and lower-middle income countries: A systematic review.

Autor: Khan T; School of Medical Science & Technology, Indian Institute of Technology, Kharagpur, India., Malik S; School of Medical Science & Technology, Indian Institute of Technology, Kharagpur, India., Rafeekh L; School of Medical Science & Technology, Indian Institute of Technology, Kharagpur, India., Halder S; School of Medical Science & Technology, Indian Institute of Technology, Kharagpur, India., Desai S; Population Council Institute, New Delhi, India., Das Bhattacharya S; School of Medical Science & Technology, Indian Institute of Technology, Kharagpur, India.
Jazyk: angličtina
Zdroj: Human vaccines & immunotherapeutics [Hum Vaccin Immunother] 2024 Dec 31; Vol. 20 (1), pp. 2411823. Date of Electronic Publication: 2024 Oct 29.
DOI: 10.1080/21645515.2024.2411823
Abstrakt: Maternal immunization (MI) is an emerging strategy to combat infant mortality in low-income (LIC) and lower-middle income countries (LMIC). We conducted a systematic review to identify the facilitators and barriers to MI and strategies that improve uptake in LICs and LMICs. We searched PubMed, Cochrane Library, and Scopus for quantitative, qualitative, and mixed-methods studies published in English from January 1, 2011, to October 31, 2021, from all LICs and LMICs. Data was appraised using the Mixed Methods Appraisal Tool. 55 studies were included. The major barriers were low knowledge and concern of vaccine safety among pregnant women and healthcare providers (HCP). HCP's recommendation, maternal knowledge, vaccine confidence and ≥4 antenatal care (ANC) visits facilitated uptake. The key strategies encompassed health financing, reminders, intersectoral coordination, integration, community engagement, capacity building, and education. Community-based delivery models were effective. Tailored programs are needed to improve ANC access, and educate pregnant women and HCPs.
Databáze: MEDLINE