Leveraging the versatile properties of bacterial spores in materials.

Autor: Kummetha LR; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Van der Maasweg 9, Delft 2629, HZ, the Netherlands., Oh JJ; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Van der Maasweg 9, Delft 2629, HZ, the Netherlands. Electronic address: J.J.Oh@tudelft.nl., van der Linden FH; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Van der Maasweg 9, Delft 2629, HZ, the Netherlands., Aubin-Tam ME; Department of Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, Van der Maasweg 9, Delft 2629, HZ, the Netherlands. Electronic address: M.E.Aubin-Tam@tudelft.nl.
Jazyk: angličtina
Zdroj: Trends in biotechnology [Trends Biotechnol] 2024 Oct 29. Date of Electronic Publication: 2024 Oct 29.
DOI: 10.1016/j.tibtech.2024.09.018
Abstrakt: Inspired by biological functions of living systems, researchers have engineered cells as independent functional materials or integrated them within a natural or synthetic matrix to create engineered living materials (ELMs). However, the 'livingness' of cells in such materials poses serious drawbacks, such as a short lifespan and the need for cold-chain logistics. Bacterial spores have emerged as a game changer to bypass these shortcomings as a result of their intrinsic dormancy and resistance against harsh conditions. Emerging synthetic biology tools tailored for engineering spores and better understanding of their physical properties have led to novel applications of spore-based materials. Here, we review recent advances in such materials and discuss future challenges for the development of time- and cost-efficient spore-based materials with high performance.
Competing Interests: Declaration of interests The authors declare no competing interests.
(Copyright © 2024 The Author(s). Published by Elsevier Ltd.. All rights reserved.)
Databáze: MEDLINE
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