Clinical characteristics and decortication outcomes of bacterial, tuberculous and fungal pleural infection.

Autor: Lin CM; Division of Thoracic Surgery, Department of Surgery, and., Chen YL; Surgery Clinical Research Center, Changhua Christian Hospital, Changhua City, Taiwan., Cheng YF; Division of Thoracic Surgery, Department of Surgery, and., Cheng CY; Division of Thoracic Surgery, Department of Surgery, and, Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan., Huang CL; Division of Thoracic Surgery, Department of Surgery, and., Hung WH; Division of Thoracic Surgery, Department of Surgery, and., Wang BY; Division of Thoracic Surgery, Department of Surgery, and, Department of Post-Baccalaureate Medicine, College of Medicine, National Chung Hsing University, Taichung, Taiwan.
Jazyk: angličtina
Zdroj: The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease [Int J Tuberc Lung Dis] 2024 Nov 01; Vol. 28 (11), pp. 541-546.
DOI: 10.5588/ijtld.24.0146
Abstrakt:

BACKGROUND

Pleural infection leading to empyema is a severe condition marked by accumulated infected fluid in the pleural space. Pneumonia with parapneumonic effusion is its most common precursor. The global incidence of pleural infections has increased significantly, with existing literature mainly focusing on bacterial empyema, leaving a gap in comparative analyses.

METHOD

A retrospective review was conducted on 561 cases of bacterial, tuberculous, and fungal empyema over a 10-year period. The study compared and analysed overall survival rates, 30-day mortality rates after surgery, and clinical characteristics.

RESULTS

The three empyema groups displayed distinct clinical characteristics. Fungal empyema had the worst overall survival compared to bacterial and tuberculous empyema, which had similar survival rates based on 30-day and 2-year mortality. Fungal empyema, advanced age, and high Charlson Comorbidity Index (CCI) score were independent predictors of poor prognosis.

CONCLUSION

Fungal empyema has the highest mortality rate post-decortication surgery. Advanced age and high CCI score are independent predictors of poor prognosis.
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Databáze: MEDLINE