Cytomorphological Spectrum of Hepatic Lesions on Ultrasonography (USG) or CT-Guided Fine-Needle Aspiration Cytology (FNAC) in a Tertiary Care Centre, Rajendra Institute of Medical Sciences (RIMS), Ranchi, Jharkhand, India.

Autor:	Kumari Gupta S; Pathology, Rajendra Institute of Medical Sciences, Ranchi, IND., Ashu T; Pathology, Rajendra Institute of Medical Sciences, Ranchi, IND., Bharti M; Pathology, Sheikh Bhikhari Medical College, Hazaribagh, IND., Paswan MK; Pathology, Rajendra Institute of Medical Sciences, Ranchi, IND., Sindhu VS; Pathology, Rajendra Institute of Medical Sciences, Ranchi, IND., N V; Community Medicine, Rajendra Institute of Medical Sciences, Ranchi, IND.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2024 Sep 26; Vol. 16 (9), pp. e70269. Date of Electronic Publication: 2024 Sep 26 (Print Publication: 2024).
DOI:	10.7759/cureus.70269
Abstrakt:	Background Ultrasonography (USG)-guided fine-needle aspiration cytology (FNAC) of the liver is a primary diagnostic procedure for primary and metastatic hepatic lesions. Despite histopathology being the gold standard, the outcomes of ultrasound-guided fine needle aspiration cytology are encouraging. Aims and objective The purpose of the study is to determine the diagnostic utility of ultrasonography (USG) or computerized tomography (CT)-guided FNAC in the detection of liver lesions, to investigate cytomorphological patterns of liver lesions identified by guided FNAC, and, wherever feasible, to correlate FNAC diagnosis with histopathology and imaging modalities. Materials and methods This was a hospital-based observational study of 62 patients carried out in the Department of Pathology, Rajendra Institute of Medical Sciences (RIMS) Ranchi during a period of 1.5 years from August 2020 to February 2022. The patients with suspected hepatic lesions were subjected to ultrasound-guided or CT-guided fine needle aspiration cytology (FNAC) following clinical and radiological evaluation and cytomorphological features were analyzed. Results Cyto-morphological diagnosis of 62 cases was categorized into 19 (30.64%) non-neoplastic lesions and 43 (69.35%) malignant neoplastic lesions. The different neoplastic lesions were 17 (27.41%) hepatocellular carcinoma, 1 (1.61%) hepatoblastoma, 1 (1.61%) cholangiocarcinoma, 23 (37.09%) metastatic adenocarcinoma and one case (1.61%) of unclassified malignancy. Histopathological correlation for confirming the diagnosis could be done in 33 malignant neoplastic lesions and the concordance rate of FNAC with respect to histopathological examination (HPE) was 92.11%. Overall diagnostic accuracy of the FNAC of liver to detect malignant lesions was 98.39%. Conclusion Compared to ultrasonography alone, ultrasound or CT-guided fine needle aspiration of the liver has a more promising role in the diagnosis and classification of hepatic lesions as it demands a higher level of precision to achieve diagnostic accuracy. Competing Interests: Human subjects: Consent was obtained or waived by all participants in this study. Institutional Ethics Committee, Rajendra Institute of Medical Sciences, Ranchi issued approval 247. This is to certify that the Institutional Ethics Committee, Rajendra Institute of Medical Sciences, Ranchi approves and grants permission for academic and scientific work on the thesis entitled "CYTOMORPHOLOGICAL SPECTRUM OF LIVER LESIONS ON USG AND CT GUIDED FNAC IN A TERTIARY CARE CENTRE, JHARKHAND" done by Dr. Monika Bharti, Junior Resident (Academic), Rajendra Institute of Medical Sciences, Ranchi in the Department of Pathology, Session 2020-2023, under the guidance of Dr. Rabindra Kumar Singh, Associate Professor, Department of Pathology, Rajendra Institute of Medical Sciences, Ranchi. Memo no.:247 Dated on 05.06.2021. Animal subjects: All authors have confirmed that this study did not involve animal subjects or tissue. Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Kumari Gupta et al.)
Databáze:	MEDLINE
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