The Efficacy of Aloe vera Against Enterococcus faecalis as an Intracanal Medicament: A Systematic Review and Meta-Analysis.
| Autor: | Bukhari SH; Department of Conservative Dentistry and Endodontics, Manav Rachna Dental College, Faridabad, IND., Abraham D; Department of Conservative Dentistry and Endodontics, Manav Rachna Dental College, Faridabad, IND., Mahesh S; Department of Microbiology, Manav Rachna Dental College, Faridabad, IND. |
|---|---|
| Jazyk: | angličtina |
| Zdroj: | Cureus [Cureus] 2024 Sep 25; Vol. 16 (9), pp. e70140. Date of Electronic Publication: 2024 Sep 25 (Print Publication: 2024). |
| DOI: | 10.7759/cureus.70140 |
| Abstrakt: | Calcium hydroxide (CaOH) is commonly used as an intracanal medicament due to its antimicrobial properties; its antibacterial property depends on the release of hydroxyl ions. By analyzing experimental in vitro studies related to the research question, many studies carried out bacterial inoculation on extracted human teeth or laboratory Petri dishes. This review article seeks to assess the antimicrobial efficacy of Aloe vera (AV) against Enterococcus faecalis in comparison to CaOH as an intracanal medicament. After being retrieved from databases such as PubMed, Scopus, the Cochrane Library, and EBSCOhost, publications from 2013 to 2024 were screened against our inclusion criteria. As a result, seven papers were included in the systematic review and four in the meta-analysis. Using a meta-analysis (Stata software version 16.0, StataCorp LLC, College Station, TX) to compare colony-forming units (CFUs) formed by CaOH and AV, forest plots were created to record the specimen size, mean, and standard deviation value of the outcome in CFU, at 95% confidence intervals. AV exhibits bactericidal qualities that are equal to or comparable to those of CaOH. AV displayed a nonsignificantly reduced CFU count than CaOH in a meta-analysis (p > 0.05). In summary, AV exhibits antibacterial/antimicrobial capabilities against E. faecalis that are equal to or comparable to CaOH. Competing Interests: Conflicts of interest: In compliance with the ICMJE uniform disclosure form, all authors declare the following: Payment/services info: All authors have declared that no financial support was received from any organization for the submitted work. Financial relationships: All authors have declared that they have no financial relationships at present or within the previous three years with any organizations that might have an interest in the submitted work. Other relationships: All authors have declared that there are no other relationships or activities that could appear to have influenced the submitted work. (Copyright © 2024, Bukhari et al.) |
| Databáze: | MEDLINE |
| Externí odkaz: |
|