Examining the Measurement Equivalence of Alzheimer Disease Research Centers' Neuropsychological Test Battery (Version 3) Between Singapore and US Samples.

Autor:	Tay SY; Department of Psychology, Singapore General Hospital., Koay WI; Department of Psychology, Singapore General Hospital., Ting SKS; Department of Neurology, National Neuroscience Institute, Singapore General Hospital., Liew TM; Department of Psychiatry, Singapore General Hospital.; SingHealth Duke-NUS Medicine Academic Clinical Programme, Duke-NUS Medical School.; Health Services and Systems Research, Duke-NUS Medical School.
Jazyk:	angličtina
Zdroj:	Alzheimer disease and associated disorders [Alzheimer Dis Assoc Disord] 2024 Oct-Dec 01; Vol. 38 (4), pp. 319-327. Date of Electronic Publication: 2024 Oct 28.
DOI:	10.1097/WAD.0000000000000649
Abstrakt:	Purpose: Standardization of neuropsychological tests is crucial for consistency in cognitive assessment, as well as for validity and comparability of results across different populations. We examined the applicability and measurement equivalence of the Alzheimer Disease Research Centers' Neuropsychological Test Battery (version 3) (ADRC-NTB3) in Singapore. Methods: The ADRC-NTB3 was administered to 978 older persons with normal cognition in Singapore. To provide comparison between Singapore and US samples, a US sample with similar profile was retrieved from the National Alzheimer Coordinating Center (NACC) database. Patients: Scores were compared with 1853 participants with similar profile from the United States. Score-difference between the populations was computed using multiple linear regression (adjusted for covariates), with equivalent score considered present when 90% CI of the score-difference fell within the predefined margin of equivalence. Results: Tasks assessing for memory, processing speed, and executive functioning showed equivalence in scores between US and Singapore samples (adjusted-score difference=-0.94 to 0.09). Singapore sample performed marginally better on the visuospatial task (adjusted-score difference=0.50), but poorer on the language task (adjusted-score difference=-3.22). Discussion: Nonequivalence of visuospatial and language tasks, which may increase potential misinterpretation of cognitive profiles and misdiagnosis, are related to educational and cultural differences. This highlights the need for different normative data for more accurate diagnostic accuracy as well as research priorities. Competing Interests: T.M.L. has provided consultation to Lundbeck. The remaining authors declare no conflicts of interest. (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
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